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Step 3 Prep Course Created by Yale Students Who Scored Perfect. Includes Online Course, Qbank, Flashcards, EKG

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Build a strong foundation in essential clinical concepts for disease diagnosis, treatment, and prevention. This course provides focused, high-quality content to help you master key material without feeling overloaded.

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Practice high-yield clinical concepts through detailed, case-based questions. Organized by chapter, the Qbank strengthens your ability to recall and apply knowledge for real-world diagnosis and management, increasing your exam confidence and speed.

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Quickly review essential clinical topics with concise flashcards. These high-yield tools are designed to reinforce learning anytime, boosting retention of critical information and enhancing your performance on Step 3.

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Master the fundamentals of EKG, including key components and interpretations. Develop the expertise to diagnose and treat various cardiac conditions using EKG tracings.

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Step 3 Course Review

Core Clinical Principles Master the application of clinical knowledge with focused, high-yield content on essential concepts for effective patient care.

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In-Depth Clinical Insights Case-based questions and visual aids deepen your understanding of critical medical concepts, enhancing clinical reasoning and decision-making.

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Complete Step 3 online prep course review

Step 3 Exam Preparation

Comprehensive Qbank Coverage Practice a wide range of clinical scenarios with detailed, case-based questions, ensuring thorough review across essential areas of medicine.

High-Yield Clinical Questions Questions are designed to emphasize key clinical concepts, boosting recall and application for effective diagnosis and management in real-world settings.

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Flashcard 1 of 150

A 71-year-old male presents to the emergency department due to otalgia 

  • Patient complains of constant left ear pain for the past week 
  • Pain is exacerbated by chewing and worse at night. Associated with yellow drainage from the left ear 
  • Past medical history includes hypertension, multiple sclerosis, and type II diabetes mellitus 
  • On examination there is granulation tissue in the external auditory canal. Smoothing of the left side of the brow and flattening of the left nasolabial fold are noted.

What is the most likely diagnosis and its management?

Answer

Diagnosis: Malignant otitis externa
Management: Intravenous antipseudomonal antibiotic

Explanation

Malignant otitis externa is an invasive infection of the external ear and skull base caused by pseudomonas aeruginosa. It mostly affects elderly immunocompromised patients with diabetes mellitus. Malignant otitis externa presents with severe otalgia and otorrhea. The pain is usually worse at night and is exacerbated by chewing. Otoscopic examination often reveals edema and granulation in the external auditory canal. Conductive hearing loss is common. Erythema, edema, and tenderness of the periauricular tissues may be present. Complications of otitis externa include osteomyelitis of the skull base and temporomandibular joint, sinus thrombophlebitis, brain abscess, and meningitis. Cranial nerve involvement occurs in 50% of patients and the facial nerve is most commonly affected. Cranial nerves VI, IX, X, XI, and XII may also be affected. The diagnosis is suspected based on clinical findings and can be confirmed with imaging. Computed tomography (CT) scanning is the preferred imaging modality to assess the extent of infection and presence of bone erosion. All patients should be treated with intravenous antipseudomonal antibiotics. Ciprofloxacin is the initial antibiotic of choice. Alternatives include cefepime, ceftazidime, ticarcillin, and piperacillin-tazobactam. Surgical debridement may be necessary for abscess drainage or removal of bony sequestrum.

Workup : Clinical diagnosis. Culture of ear canal drainage. CT scan to evaluate bone erosion

Management :Intravenous antipseudomonal antibiotics

Miscellaneous :Squamous cell carcinoma (SCC) of the temporal bone can have a similar presentation. If there is suspicion for SCC, bone biopsy is necessary for a definitive diagnosis.

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Flashcard 2 of 150

A 50-year-old male presents to the emergency department due to cough 

  • Cough began 4 weeks ago and is productive of thick, foul-smelling sputum 
  • Associated symptoms include shortness of breath, fever, and malaise 
  • Medical history is significant for coronary artery disease, COPD, and alcohol use disorder 
  • Vital signs are T 101.5 F, HR 100/min, BP 128/70 mm Hg, and RR 28/min

Chest X-ray is shown below

What is the most likely diagnosis and its management?

Answer

Diagnosis: Lung abscess
Management: Intravenous antibiotics (ampicillin-sulbactam)

Explanation

Lung abscess is a localized purulent infection of the lung parenchyma. Lung abscess can occur due to hematogenous spread, aspiration, direct extension of local infection, and bronchial obstruction. Risk factors include alcohol abuse, dysphagia, periodontal disease, seizures, drug abuse, immunosuppression, and diabetes mellitus. The clinical presentation of lung abscess is similar to pneumonia although it has a more insidious onset. Symptoms include cough productive of foul-smelling phlegm, fever, chills, and shortness of breath. The diagnosis is made based on clinical findings and imaging. Chest radiographs typically show a cavitary lesion with an air fluid level. Computed tomography (CT) is often performed to evaluate for associated lung pathology such as consolidation, obstruction, and empyema which may not be identified on plain radiographs. Management of lung abscess include supportive care and antibiotics. Initial empiric antibiotics should provide broad coverage that includes anaerobes. Ampicillin-Sulbactam or a carbapenem are appropriate for initial management. Antibiotics may be deescalated once culture results are avail able. If there is inadequate response to antibiotic therapy, drainage of the abscess is required.

Workup : Chest X-ray

Management : Intravenous antibiotics (ampicillin-sulbactam)

Miscellaneous : Other causes of cavitary lung lesions include cavitary tumors, mycobacterial infection, pulmonary infarction, vasculitis, and infected bullae.

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Flashcard 3 of 150

A 29-year-old-woman is brought to the emergency department by her husband because of a 1 hour history of tinnitus, nausea, and vomiting

  • Vital signs on presentation are temperature 102 F, heart rate 95/min, blood pressure 130/95 mmHg, and respiratory rate 26/min
  • Thirty minutes after presentation the patient becomes lethargic 
  • Her husband states that she was in her normal state of health and asymptomatic two hours ago
  • Medical history includes depression treated with escitalopram. 
  • Results of an ABG taken on admission are as follows:

pCO2: 25 mmHg

HCO3: 18 mmol/L

pO2: 110 mmHg

pH: 7.46

What is the most likely diagnosis and its management?

Answer

Diagnosis: Salicylate toxicity
Management: Fluid resuscitation, IV bicarbonate, and consultation with nephrology for potential hemodialysis.

Explanation

Aspirin, the most commonly used salicylate, is used as an anti-inflammatory, antipyretic, and as an anti-thrombotic medication. Due to its widespread use, accidental or intentional overdoses are not uncommon; there’s approximately 30000 reported cases each year in the United States. Most cases are typically mild and present with tinnitus, vertigo, nausea, and vomiting.

In extreme cases, the mortality rate can reach up to 15% due to the severe metabolic derangements. Aspirin can cause multiple acid base disturbance owing to its unique mechanisms of action. The earliest acid base abnormality seen in aspirin toxicity is a primary respiratory alkalosis. This is caused by aspirins direct effect on the breathing center in the medulla leading to hyperpnea and a drop in pCO2. After this initial disturbance, an anion gap metabolic acidosis usually follows. This is caused by the accumulation of organic acids due to aspirins disruption of multiple metabolic pathways such as the Krebs cycle and oxidative phosphorylation. Due to these two mechanisms, the most common disturbance seen in aspirin overdose is a mixed primary respiratory alkalosis and metabolic anion gap acidosis. The last abnormality that can occur later in the course of acute profound toxicity is respiratory acidosis. Other symptoms that occur in severe toxicity include mental status alterations, pulmonary edema, cerebral edema, hyperthermia, hypovolemia, and hypokalemia.

Aspirin overdose management should always begin with stabilization of the airway, breathing, and circulation. It’s important to note that tracheal intubation should be avoided if possible; the interruption of aspirin induced-hyperpnea, especially the period of apnea during the apnea period of intubation initiation, can dramatically worsen the patient’s respiratory acidosis and central nervous system toxicity. Thus, intubation should be reserved for patients with hypoventilation. Aggressive volume resuscitation is indicated in hypovolemic patients unless there is evidence of pulmonary or cerebral edema. Decontamination with activated charcoal is indicated in patients who present within two hours of ingestion.

The mainstay of aspirin toxicity management is urine and serum alkalization. This is achieved with IV sodium bicarbonate. Potassium should also be administered along with sodium bicarbonate to prevent hypokalemia. Hemodialysis may be indicated if any of the following are present:

  1. Altered mental status 
  2. Pulmonary or cerebral edema
  3. Kidney dysfunction (Cr>176mM or GFR<45 ml/min/1.73m^2 
  4. Ph<7.20 
  5. Salicylate level >7.2mM 
  6. Hypervolemia
  7. Treatment failure

Workup : Diagnosis is established based on clinical presentation and history of ingestion. Salicylate level should be obtained

Management : Fluid resuscitation, IV bicarbonate, and consultation with nephrology for potential hemodialysis

Miscellaneous : Hyperthermia seen in severe salicylate toxicity is caused by uncoupling of oxidative phosphorylation

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Flashcard 4 of 150

A 4-year-old male is brought to the emergency department after a seizure 

  • Mother states that while playing he collapsed and had jerking movements of the upper and lower extremities 
  • The seizure lasted three minutes and resolved spontaneously prior to presentation 
  • Patient was recently diagnosed with RSV bronchitis and is being managed conservatively 
  • Vitals are T 102.3 F, HR 140 bpm, BP 97/60 mmHg, and RR 24/min
  • On examination he is awake but irritable. There are no focal neurological deficits

What is the most likely diagnosis and its management?

Answer

Diagnosis: Simple febrile seizure
Management: Antipyretics, observation

Explanation

Febrile seizures are relatively common in children under five years of age. Febrile seizure is defined as a convulsion that is associated with a temperature > 100.4 F in a child under five years of age that occurs in the absence of central nervous system (CNS) infection and metabolic abnormalities that can cause convulsions. Febrile seizures are broadly classified as either simple or complex.

Simple febrile seizure:

  • Generalized seizure
  • Duration less than 15 minutes 
  • One episode within a 24-hour period

The most common cause of febrile seizures is infection (viral is more common than bacterial). Patients will often present with signs and symptoms of an upper respiratory illness. Febrile seizure is a clinical diagnosis. Additional workup is generally not necessary in the case of simple febrile seizure if the etiology is known (as in this case). The workup of complex febrile seizures is case dependent and may include a lumbar puncture, neuroimaging, and electroencephalography. Management of simple febrile seizures consists of antipyretics and observation. Benzodiazepines are indicated if seizure activity lasts longer the 5 minutes.

Workup : Clinical diagnosis

Management : Antipyretics

Miscellaneous : Lumbar puncture should be performed in children between 6 and 12 months who have deficient or unknown immunization for Hib or S. Pneumoniae

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Flashcard 5 of 150

A 13-year-old male presents to the emergency department after a fall from a tree

  • Fell from a height of approximately 6 feet 4 hours prior to presentation 
  • He landed on his left side and does not recall any head trauma 
  • He complains of pain over the left forearm and left side of the face
  • Examination is remarkable for abrasions over the extremities and face. The left forearm is firm, erythematous, and tender to palpation. Movement of the wrist causes severe forearm pain. The left radial pulse is palpable. Sensation of the left upper extremity is intact.

X-ray of the left forearm is shown below

What is the most likely diagnosis and its management?

Answer

Diagnosis: Compartment syndrome
Management: Fasciotomy

Explanation

Compartment syndrome is a surgical emergency characterized by increased intracompartmental pressure (ICP) within an osteofascial compartment leading to tissue ischemia. Compartment syndrome is most often caused by long bone fractures. Other causes include crush injury, penetrating trauma, animal bits/stings, and constrictive bandages or casts. Compartments of the forearm and leg are most frequently affected; however, it may also occur in the hand, arm, thigh, or foot. As the intracompartmental pressure surpasses the diastolic blood pressure, arteriole and capillary perfusion is restricted and the muscles within the compartment become ischemic. The systolic blood pressure may still be sufficient to force blood through the arteries of the compartment, producing palpable pulses. Loss of distal pulses is a late sign of compartment syndrome and usually indicates severe muscle damage and a poor prognosis. Early signs and symptoms of compartment syndrome include pain out of proportion to the injury, paresthesia, and pain with passive stretch of the muscles in the compartment. Paralysis, pallor, and loss of pulses are late signs. Compartment syndrome is a clinical diagnosis. If available, a manometer can be used to measure the compartment pressure. The delta pressure is calculated by subtracting the measured compartment pressure from the diastolic blood pressure. A delta pressure less than 30 mm Hg is consistent with compartment syndrome. Definitive management of compartment syndrome often requires fasciotomy. If significant muscle damage has already occured, amputation may be necessary.

Workup : Clinical diagnosis, compartment pressure

Management :Fasciotomy

Miscellaneous : The five P’s (pain, pallor, paresthesias, pulselessness, and poikilothermia) of arterial insufficiency are uncommon in compartment syndrome.

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Female Reproductive System Content Review 9% - 13%

 

In the reproductive system, the UMock USMLE® Step 1 prep course covers the male and female reproductive system as well as pregnancy, childbirth, and the puerperium. The course provides high-yield topics concentrated on clear and concise explanations to help you understand and apply concepts to clinical scenarios associated with the hormonal pathways of the male and female reproductive systems.

The course integrates concepts with high quality microscopic views and diagnostic images to help you improve recall of normal and abnormal processes in disease and apply it to clinical scenarios like you’ll see on the exam.

  • Ovaries
  • Breast
  • Vulva & Vagina
  • Uterine Cervix
  • Uterine Corpus
  • Fallopian Tubes
  • Disorders of Pregnancy
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Endocrine System Content Review 9% - 13%

 

The UMock USMLE® Step 1 prep course combines concise high yield topics with detailed diagrams covering normal and abnormal processes of endocrine-specific pathologies and physiologies. The course helps you gain a clear understanding of how to apply concepts to clinical scenarios for keeping hormone levels in balance, diagnostic testing, treatment, and management.

The course includes descriptive illustrations, microscopic views, images, and graphs highlighting heavily test exam content to help you gain a full understanding of applying concepts for normal and abnormal processes of the endocrine system.

  • Endocrine Pancreas
  • Endocrine of Pituitary
  • Endocrine of Thyroid Gland
  • Endocrine of Adrenal Glands
  • Endocrine of Parathyroid Glands
  • Multiple Endocrine neoplasia (MEN) Syndrome
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Dermatology Content Review 6% - 10%

 

In Dermatology, the UMock USMLE® Step 1 prep course gives you concise, high yield topics to help you understand how to apply basic concepts to clinical scenarios in comparing similar pathologies based on the morphology and distribution of conditions.

Every topic is covered for both normal and abnormal body-system processes with high quality microscopic views and gross images to help you visually understand the application of medicine specific to diseases in skin and subcutaneous tissue.

  • Pruritus
  • Urticaria
  • Common Rashes
  • Infestations
  • Bites & Stings
  • Hair Disorders
  • Common Neoplasms
  • Acneiform Eruptions
  • Common Skin Infections
  • Cuts, Scrapes, & Burns
  • Foot and Leg Ulcers
  • Nail Disorders
  • Disorders of Mucous Membranes
  • Autoimmune Blistering Diseases
  • Therapeutic Principles in Dermatology
  • Dermatologic Urgencies and Emergencies
  • Cutaneous Manifestations of Internal Disease
  • Dermatologic Problems of Special Populations
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Nervous System Content Review 4% to 7%

 

Exam items covering the nervous system represent about 4-7% of test questions. The UMock Step 1 Prep Course clearly explains gross anatomy and neuroanatomy and normal and abnormal processes from this area, including

  • Embryonic development
  • Fetal maturation
  • Perinatal changes
  • Neural tube derivatives
  • Cerebral ventricles
  • Neural crest derivatives
  • Organ structure & function
  • Cell & tissue structure & function
  • Repair
  • Regeneration
  • Changes associated with life stages
  • Infectious
  • Immunologic
  • Inflammatory disorders
  • Neoplasms
  • Cerebrovascular disease
  • Disorders related to spinal cord
  • Spine
  • Spinal nerve roots
  • Cranial & peripheral nerve disorders
  • Neurologic pain syndromes
  • Degenerative disorders
  • Global cerebral dysfunction
  • Neuromuscular
  • Metabolic disorders
  • Paroxysmal disorders
  • Sleep disorders
  • Traumatic & mechanical disorders
  • Increased intracranial pressure
  • Congenital disorders
  • Disorders of the eye & eyelid
  • Disorders of the ear
  • Movement disorders
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Rheumatology and Musculoskeletal Content Review 6% - 10%

 

The UMock USMLE® Step 1 prep course provides the most valuable exam information with a complete and concise review of high-yield topics to help you quickly understand and apply knowledge to clinical scenarios covering the diagnosis of joint pathologies, and anatomical paths of distal branches and the muscles that they innervate.

The course features detailed tables and high quality radiologic and gross images to help you conceptualize the application of medicine for normal and abnormal body system processes and pathologies in rheumatology and the musculoskeletal system.

  • Diseases of Skeletal Muscle
  • Diseases of Bone
  • Diseases of Joints
  • Soft-Tissue Tumors
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Behavioral Science Content Review 8% to 13%

 

Behavioral science accounts for roughly 8-13% of exam questions. The UMock USMLE® Step 1 prep course helps you clarify difficult concepts in the mind-body relationship, and understand how to apply DSM-IV and DSM-5 diagnostic criteria in the manifestations of psychological disorders to various clinical scenarios with a high-yield, concise review of concepts covering every topic for normal and abnormal processes.

The course includes descriptive diagrams, tables, and images to provide a concentrated review of material to help you fully understand the application of behavioral science to clinical medicine.

  • Sexuality
  • Learning Theory
  • Beginning of Life
  • Anxiety Disorders
  • Aggression & Abuse
  • Psychosomatic Medicine
  • Somatic Symptom Disorders
  • Obsessive-Compulsive Disorders
  • Trauma & Stressor-Related Disorders
  • Substance-related Disorders
  • Sleep & Sleep-wake Disorders
  • Psychological Therapies
  • Family, Culture, & Illness
  • Psychiatrics Disorders in Children
  • Aging, Death, & Bereavement
  • School Age, Adolescence, & Adulthood
  • Psychoanalytic Theory & Defense Mechanisms
  • Depressive Disorders & Bipolar Disorders
  • Schizophrenia Spectrum & other Psychotic Disorders
  • Clinical Assessment of Patients with Behavioral Symptoms
  • Biological Assessment of Patients with Psychiatric Symptoms
  • Neurocognitive, Personality, Dissociative & Eating Disorders
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Embryology Content Review 11% - 15%

 

In Embryology, the UMock USMLE® Step 1 prep course presents high-yield content in a concise format that helps you understand and quickly recall concepts in human development and congenital malformations, and apply the connection between embryological knowledge and clinical medicine. The course further clarifies key facts and concepts to help you maximize comprehension and visual understanding in applying concepts with high quality diagnostic, radiographic, and clinical images.

  • Skeletal System
  • Muscular System
  • Upper Limb
  • Lower Limb
  • Body Cavities
  • Pregnancy
  • Teratology
  • Head & Neck
  • Prefertilization Events
  • Human Development - Week 1
  • Human Development - Week 2
  • Embryonic Period
  • Cardiovascular System
  • Placenta & Amniotic Fluid
  • Embryology of the Ear
  • Embryology of the Eye
  • Embryology of the Nervous
  • Embryology of the Digestive
  • Embryology of the Respiratory
  • Urinary System
  • Female Reproductive System
  • Male Reproductive System
  • Integumentary System
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Women’s Health and Pregnancy Content Review 3% to 5%

 

The musculoskeletal system accounts for roughly 3-5% of the exam. Learn everything covered on this section of the exam for normal and abnormal process with the UMock Step 1 Prep Course:

  • Tendon
  • Repair
  • Joints
  • Usage
  • Muscles
  • Cartilage
  • Arthritis
  • Infectious
  • Regeneration
  • Blood supply
  • Gross anatomy
  • Neoplasms
  • Embryonic development
  • Organ structure & function
  • Changes associated with life stages
  • Cell & tissue structure & function
  • Ligaments & fascia
  • Traumatic & mechanical disorders
  • Mechanism of the action of drugs
  • Fetal maturation & perinatal changes
  • Inflammatory & immunologic disorders
  • Adverse effects on the musculoskeletal system
  • Degenerative & metabolic disorders of bone
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Histology Content Review 8% to 13%

 

Histology makes up about 8-13% of questions on the exam. The UMock USMLE® Step 1 prep course offers a high-yield review condensed concepts format to help you better understand the relationship between cell structure and function to biological tissues, and effectively apply concepts to clinical scenarios on the exam. The course includes high quality micrographs, illustrations, and tables to further enhance your ability to quickly recall concepts and how they apply in clinical practice.

  • Cell Histology
  • Extracellular Matrix
  • Epithelia & Glands
  • Connective Tissue
  • Blood & Hemopoiesis
  • Histology Cartilage & Bone
  • Histology Muscle
  • Nervous Tissue
  • Circulatory System
  • Histology of Lymphoid
  • Histology of Endocrine
  • Histology of Skin
  • Histology of Respiratory
  • Histology of Digestive
  • Urinary Glands
  • Female Reproductive
  • Male Reproductive
  • Special Senses
  • Cavity and Alimentary Tract
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Anatomy Content Review 11% to 15%

 

In Anatomy, the UMock USMLE® Step 1 prep course presents the most important high-yield facts you need to memorize for the exam, and helps you understand and apply clinical correlations of the structure and organization of the body to clinical scenarios such as fractures, trauma, and injuries. The course is illustrated with high quality descriptive images of anatomic relationships to further enhance your ability to apply knowledge to concepts.

  • Perineum
  • Vertebral Column
  • Spinal Cord & Spinal Nerves
  • Autonomic Nervous System
  • Lymphatic System
  • Chest Wall
  • Anatomy of the Heart
  • Abdominal Wall
  • Kidney, Ureter, Bladder, & Urethra
  • Suprarenal Glands
  • Abdominal Vasculature
  • Abdominal Viscera
  • Anatomy of the Pelvis
  • Spleen
  • Female Reproductive
  • Male Reproductive
  • Anatomy of the Upper Limb
  • Anatomy of the Lower Limb
  • Anatomy of the Head
  • Anatomy of the Neck
  • Anatomy of the Eye
  • Anatomy of the Ear
  • Pleura, Tracheobronchial Tree, & Lungs
  • Sigmoid Colon, Rectum, & Anal Canal
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Neuroanatomy Content Review 9% to 13%

 

In Neuroanatomy, the UMock USMLE® Step 1 prep course provides high-yield concepts in a clear and concise presentation to help you thoroughly understand and apply concepts in clinical scenarios covering different pathways and tracts, patterns, distribution territories, and the results of lesions.

In Neurology, the UMock USMLE® Step 1 prep course offers a clear and concise approach to helping you understand and apply concepts to clinical scenarios with high yield concepts covering the relationship between nerves and neurotransmission, and neurologic disease

The course features high quality illustrations, detailed tables, and radiologic images for both normal and abnormal processes to help you better understand how to apply concepts for diagnosis, treatment and management of neurologic diseases.

  • Cerebellum
  • Neurohistology
  • Cranial nerves
  • Auditory System
  • Vestibular System
  • Cerebral Cortex
  • Visual System
  • Gross Anatomy of the Brain
  • Tracts of the Trigeminal system
  • Meninges & Cerebrospinal Fluid
  • Development of the Nervous System
  • Olfactory, Gustatory, & Limbic
  • Autonomous Nervous System
  • Neurotransmitters & Pathways
  • Diencephalon: Thalamus & Hypothalamus
  • Blood supply of the Central Nervous System
  • Tracts & Lesions of the Spinal Cord & Brainstem
  • Tracts & Lesions of the Spinal Cord & Brainstem
  • Basal Nuclei & the Extrapyramidal Motor System
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Legal and Ethics Content Review 6% to 10%

 

The UMock USMLE® Step 1 prep course gives you a clearly explained review of high-yield topics to help you understand how to apply, and make a decision in clinical scenarios involving calculated risks, promoting the patients’ best interest, and respecting the patient’s decisions about their own health. Topics from the course include:

  • Minors
  • Abortion
  • Refusing Care
  • Confidentiality
  • Informed Consent
  • Abuse & Neglect
  • Reportable Diseases
  • Ethical Principles
  • Healthcare Legislation
  • Capacity & Competency
  • Physician Assisted Suicide
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Biostatistics and Epidemiology Content Review 4% to 6%

 

Biostatistics and Epidemiology covers roughly 4-6% of exam questions. The UMock USMLE® Step 1 prep course clarifies difficult concepts with a concise review of high-yield concepts. The course eliminates excessive detail to help you memorize and understand how to efficiently identify and extract the most important information, and apply your knowledge to concepts and formulas. The course includes high quality graphs and tables that clearly illustrate the most important and heavily tested concepts you need to know how to apply for the exam, including:

  • Research Methods
  • Hypothesis Testing
  • Descriptive Statistics
  • Differential Statistics
  • Assessing the Evidence
  • Correlational & Predictive Techniques
  • Statistics in Medical Decision Making
  • Epidemiology & Population Health
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Biostatistics and Epidemiology Content Review 4% to 6%

 

Biostatistics and Epidemiology covers roughly 4-6% of exam questions. The UMock USMLE® Step 1 prep course clarifies difficult concepts with a concise review of high-yield concepts. The course eliminates excessive detail to help you memorize and understand how to efficiently identify and extract the most important information, and apply your knowledge to concepts and formulas. The course includes high quality graphs and tables that clearly illustrate the most important and heavily tested concepts you need to know how to apply for the exam, including:

  • Research Methods
  • Hypothesis Testing
  • Descriptive Statistics
  • Differential Statistics
  • Assessing the Evidence
  • Correlational & Predictive Techniques
  • Statistics in Medical Decision Making
  • Epidemiology & Population Health
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UMock Step 3 Content

Internal medicine Surgery Pediatrics
Obstetrics Gynecology Phychiatry
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Internal medicine

 
  • Gastrointestinal System
    • Introduction to gastroenterology
    • Diseases of the esophagus
    • Malabsorption
    • Diseases of the colon
    • Diseases of the anus and rectum
    • Diseases of the biliary tree
    • Diseases of the liver
    • Diseases of the pancreas
  • Endocrine System
    • Introduction to endocrinology
    • Thyroid disease
    • Hypothalamic-pituitary axis
    • Adrenal disease
    • Parathyroid disease
    • Diabetes
  • Oncology
    • Oncology review
    • Cancers by organ system

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Surgery

 
  • Basic concepts on reproduction
    • Female reproduction
    • Male reproduction
    • Fertilization
    • Infertility
    • Managing infertility
    • Contraception
  • Antenatal risks and complications
    • Spontaneous abortion
    • Ectopic pregnancy
    • Gestational trophoblastic disease
    • Placenta previa
    • Abruptio placenta
    • Incompetent cervix
    • Hyperemesis gravidarum
    • Anemia
    • Gestational diabetes mellitus
    • Hypertensive disorders
    • Cardiac disorders
    • Torch infections
    • HIV/AIDS
    • Chorioamnionitis
    • Group B streptococcus
    • Sexually transmitted infections
  • Neonatal nursing care
    • Newborn assessment
    • Immediate newborn care
    • Physical assessment
    • Pain assessment
    • Physiological changes and nursing care
    • Newborn safety
    • Newborn nutrition
    • Client education
  • Intrapartal risks and complications
    • Premature rupture of membranes
    • Cord prolapse
    • Fetal distress
    • Vena cava syndrome
    • Preterm labor
    • Precipitous labor
    • Uterine rupture
    • Amniotic fluid embolism
    • Uterine inversion
    • Intrauterine fetal demise
    • Dystocia
  • Postpartum risks and complications
    • Postpartum infections
    • Thromboembolic disorders
    • Coagulopathies
    • Postpartum hemorrhage
    • Uterine atony
    • Uterine subinvolution
    • Retained placenta
    • Hematoma and lacerations
  • Neonatal risks and complications
    • Preterm neonate
    • Small for gestational age
    • Large for gestational age
    • Transient tachypnea
    • Birth injuries / trauma
    • Hypoglycemia
    • Neonatal abstinence syndrome
    • Fetal alcohol spectrum disorder
    • Erythroblastosis fetalis
    • Mnemonics and explanation
  • Antepartum nursing care
    • Prenatal assessment
    • Physiological maternal changes
    • Psychosocial responses
    • Signs of pregnancy
    • Common discomforts of pregnancy
    • Fetal and maternal well-being assessment
    • Nutritional needs
    • Client education
  • Intrapartum nursing care
    • The labor process
    • Premonitory signs of labor
    • Electronic fetal monitoring
    • Fetal heart rate patterns
    • Paced breathing techniques
    • Stages of labor
    • Pharmacological anesthesia
    • Pharmacological analgesia
    • Obstetric procedures
  • Neonatal risks and complications
    • Preterm neonate
    • Small for gestational age
    • Large for gestational age
    • Transient tachypnea
    • Birth injuries / trauma
    • Hypoglycemia
    • Neonatal abstinence syndrome
    • Fetal alcohol spectrum disorder
    • Erythroblastosis fetalis
    • Mnemonics and explanation
  • Postpartum nursing care
    • Expected maternal changes

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Pediatric nursing Content Review

 
  • Pediatric disorders
    • Integumentary problems
    • Neurological problems
    • Eyes, ears and throat problems
    • Respiratory problems
    • Cardiovascular problems
    • Gastrointestinal problems
    • Genitourinary and renal problems
    • Hematologic problems
    • Oncologic disorders
    • Musculoskeletal problems
    • Infectious diseases
    • Mnemonics and explanation
    • Image citations
  • Pediatric nursing care
    • Considerations
    • Illness and hospitalization
    • Restraints
    • Death and dying
    • End of life care
  • Pediatric assessment
    • Pain assessment
    • Health history interview
    • Physical assessment
  • Growth and development
    • Growth patterns and trends
    • Summary of developmental theories
    • Physical growth and development
  • Health promotion
    • Nutrition, dental health, sleep and rest
    • Childhood and adolescent immunizations
    • Promoting safety
    • Play and age-appropriate activities

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Drug interactions Content Review

 
  • Overview
  • Pharmaceutical Drug Interactions
  • Pharmacodynamic Drug Interactions
  • Other Types of Drug Interactions
  • Pharmacokinetic Drug Interactions
    • Absorption
    • Distribution
    • Metabolism
    • Elimination

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Pharmacogenomics Content Review

 
  • Precision Medicine
    • Biomarkers
    • Polymorphisms
    • Polymorphism Nomenclature
    • Linkage Disequilibrium
    • Tag-SNPs
    • Phase II Polymorphisms
    • Other Testing
    • Dosing Recommendation Resources

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Critical care nursing Content Review

 
  • Fundamentals of critical care
    • Definition of critical care
    • Healthy work environment
    • Rapid response team
    • Code management
    • Basic life support
    • Chains of survival
    • Adult cardiac arrest algorithm
    • Cardiopulmonary resuscitation
    • Advanced cardiac life support
    • 2020 BLS and ACLS updates
    • Code medications
    • EKG/ECG monitoring
    • Hemodynamic monitoring
    • Ventilatory assistance
    • Airway management
    • Mechanical ventilation
  • Cardiovascular disorders
    • Basic dysrhythmias
    • Carotid artery disease
    • Pulmonary hypertension
    • Sudden cardiac death
  • Respiratory disorders
    • Acute lung failure
    • Acute respiratory distress syndrome
    • Coronavirus disease
    • Intracranial hypertension
    • Herniation syndromes
    • Status epilepticus
  • Hematologic and immunologic disorders
    • Disseminated intravascular coagulation
    • Tumor lysis syndrome
    • Heparin-induced thrombocytopenia
  • Gastrointestinal disorders
    • Acute GI bleeding
    • Variceal bleeding
  • Endocrine disorders
    • Diabetic ketoacidosis
    • Hyperglycemic hyperosmolar state
    • Hypoglycemia
  • Shock, sirs and mods
    • Types
    • Stages
    • Significant laboratory tests
    • Shock-specific assessment and interventions
    • Systemic inflammatory response syndrome
    • Multiorgan dysfunction syndrome
    • Mnemonics
    • Image citations

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Nursing pharmacology Content Review

 
  • Fundamentals of nursing Pharmacology
    • Basic principles
    • Drug regulation
    • Drug labels
    • Medication errors
    • Nursing responsibilities
    • Drug calculation
  • Drugs acting on the nervous system
    • CNS depressants
    • Muscle relaxants
    • Analgesics
    • Antimigraine agents
    • Anesthetics
    • Neuromuscular blocking agents
    • Antiseizure agents
    • Antiparkinsonism agents
    • Psychotherapeutic agents
    • Adrenergics
    • Muscarinic/ cholinergic/ cholinomimetic
    • Parasympathomimetic agents
    • Muscarinic antagonists/ anticholinergic
    • agents/ parasympatholytics
  • Antimicrobial agents
    • Key terms
    • Antibiotics
    • Antituberculous agents
    • Antifungal agents
    • Antiprotozoal agents
    • Anthelminthics
    • Ectoparasiticides
    • Antiviral agents
  • Drugs affecting the reproductive system
    • Women's health drugs
    • Men's health drugs
  • Drugs affecting the Cardiovascular system
    • Antihypertensive agents
    • Drugs for heart failure
    • Antiarrhythmic agents
    • Antianginal agents
    • Antihyperlipidemic agents
  • Drugs affecting the blood
    • Key concepts
    • Drugs affecting the formation of clots
    • Drugs used to treat anemias
  • Drugs acting on the respiratory system
    • Key concepts
    • Drugs used for managing upper respiratory system disorders
    • Drugs used for asthma and COPD
  • Drugs affecting the endocrine system
    • Key concepts
    • Antidiabetic agents
    • Glucose elevating agent
    • Drugs for thyroid disorders
    • Drugs affecting calcium levels
    • Drugs affecting hypothalamic and pituitary function
    • Drugs for adrenal cortex disorders
  • Drugs acting on the gastrointestinal tract
    • Key concepts
    • Drugs controlling gastrointestinal secretions
    • Antidiarrheals
    • Laxatives
    • Antiemetics
    • Drugs for inflammatory bowel disease
    • Drugs for irritable bowel syndrome
    • Other medications affecting the
    • gastrointestinal tract
  • Drugs acting on the renal system
    • Key concepts
    • Diuretics
    • Anti-infectives for the urinary tract
    • Antispasmodics
    • Drugs for benign prostatic hyperplasia
  • Drugs affecting the musculoskeletal system
    • Drugs for gouty arthritis
    • Skeletal muscle relaxants
    • Drugs for osteoporosis
  • Drugs for disorders of the eyes and ears
    • Common eye medications
    • Drugs for glaucoma
    • Drugs for macular degeneration
    • Common ear medications

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Nursing Skills and Therapies Content Review

 
  • Common tests and procedures
    • Specimen collection
    • Urine studies
    • Stool studies
    • Blood studies
    • Microscopic examinations
    • Fluid analysis tests
    • Radiologic studies
    • Ultrasonography
  • Intravenous therapy
    • Intravenous infusion
    • Blood transfusion
  • Promoting nutrition
    • Nutrition
    • Macronutrients
    • Micronutrients
    • Major minerals
    • Trace minerals
    • Malnutrition
    • Dietary guidelines
    • Nutrition across the lifespan
    • Texture-based therapeutic diets
    • Disease-based therapeutic diets
    • Vegetarian diets
    • Dysphagia and aspiration
    • Enteral nutrition
    • Parenteral nutrition
  • Perioperative nursing
    • Purposes of surgery
    • General classifications
    • Anesthesia
    • Preoperative phase
    • Intraoperative phase
    • Postoperative phase
  • Complementary and alternative therapies
    • Energy therapies
    • Biological-based therapies
    • Whole medical systems
    • Mind-body interventions
    • Manipulative and body-based methods
    • Mnemonics and explanation
    • Image citations

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Autoimmune Content Review

 
  • Autoimmune Disorders
    • Symptoms
    • Detection
    • Treatment
  • Rheumatoid Arthritis
    • Clinical Features
    • Diagnosis
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
    • Patient Counseling
  • Psoriasis
    • Overview
    • Presentation
    • Treatments
    • Pharmaceutical Treatments
  • Celiac Disease
    • Cause
    • Clinical Features
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
  • Multiple Sclerosis
    • Clinical Features
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
    • Symptom Control Treatments
    • Patient Counseling
  • Sjogren’s Syndrome
    • Overview
    • Clinical Presentation
    • Dry Mouth Treatments
    • Dry Eye Treatments
  • Myasthenia Gravis
    • Symptoms
    • Treatment
    • Drugs that Exacerbate Myasthenia Gravis
  • Systemic Lupus Erythematosus
    • Disease Course
    • Activating Factors
    • Drug Induced Lupus Erythematosus
    • Clinical Features
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
  • Raynaud’s Phenomenon
    • Overview
    • Presentation and Symptoms
    • Pharmaceutical Treatment
    • Drug-Induced Raynaud’s

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The Respiratory System Content Review

 
  • Overview
    • Gas Exchange
    • Other Organs Involved
  • Anatomy and Function
    • Upper Respiratory Tract
    • Lower Respiratory Tract
  • Drug Delivery
    • Systemic Delivery
    • Localized Delivery
  • Lung Capacities
    • Spirometry
  • Homeostatic Acid-Base Balance
    • Identifying Lab Values
    • Acidosis
    • Alkalosis
    • Clinical Features
    • Respiratory Compensation
    • Renal Compensation
    • Anion Gap

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Pulmonary Vascular Resistance Content Review

 
  • Overview
    • Poiseuille’s Law
    • Mechanisms
    • Pathophysiology
    • Clinical Presentation
  • Regulation of Pulmonary Vascular Resistance

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Pulmonary Hypertension Content Review

 
  • Overview
    • Classifications
  • Clinical Features of Pulmonary Arterial Hypertension
    • Symptom Classifications
    • Treatment / Cure
  • Pathophysiology
    • Imbalance of Endogenous Vaso-modulators
    • Imbalance of Cell Regulation
    • Diagnosis
  • Non-Pharmaceutical Treatments
  • Pharmaceutical Treatments
    • Immunizations
    • Supportive Therapies
    • Soluble Guanylate Cyclase Stimulator
    • Phosphodiesterase-5 Inhibitors
    • Receptor Agonists and Proteinoids
    • Endothelin Receptor Antagonists
  • Pulmonary Fibrosis
    • Overview
    • Clinical Features
  • Drug Interactions
    • Soluble Guanylate Cyclase Stimulator: Riociguat
    • Phosphodiesterase-5 Inhibitors
    • Prostacyclin Receptor Agonists and Prostacyclin Analogs
    • Endothelin Receptor Antagonists

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Obstructive Diseases Content Review

 
  • COPD
    • Overview
    • Classification
    • Causes
    • Diagnosis
    • Clinical Features
    • Asthma Classifications
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
    • Theophylline, Leukotriene Receptor Antagonists, mAbs
    • Additional Treatments
    • Special Patient Populations and Circumstances
  • Emphysema
    • Overview

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Cystic Fibrosis Content Review

 
  • Overview
    • Pathophysiology
    • Incidence
    • Inheritance
    • CFTR Mutation
    • Clinical Features
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
    • Patient Counseling

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Acute and Critical Care Content Review

 
  • Overview
    • Acute Care
    • Intensive Care Unit
  • Venous Thromboembolism
    • Causes
    • Deep Vein Thrombosis
    • Clinical Presentation
    • Comorbidities
    • Prevention
  • Ventilators
    • Ventilator-Induced Lung Injury
    • Ventilator-Induced Infections
  • Common Conditions in the Intensive Care Unit
    • Pain
    • Delirium
    • Agitation
  • More Drugs used in the ICU and the Operating Room
    • Anesthetics
    • Neuromuscular Blocking Drugs
    • Hemostatic Drugs
  • Pulmonary Embolism
    • Adverse Side Effects

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The Heart Content Review

 
  • Anatomy and Function
  • Flow of Blood

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Dyslipidemia Content Review

 
  • Non-Pharmaceutical Treatments
  • Pharmaceutical Treatments
    • Concerns
    • Lomitapide
    • Mipomersen
    • Ezetimibe
    • Statins
    • Fish Oils
    • Peroxisome Proliferator Receptor Alpha Activators
    • Bile Acid Sequestrants
    • Proprotein Convertase Subtilisin Kexin Type 9 Inhibitors
    • Niacin
  • Overview
    • Classifications
  • Diagnostic Criteria
    • Clinical Features

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Hypertension Content Review

 
  • Overview
  • Clinical Features
    • Pathophysiology
    • Compensation
  • Diagnostic Criteria
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    • Drug Interactions
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    • Drug Interactions
    • Patient Counseling
  • Diuretics
    • Thiazide-Type
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  • Beta-Blockers
    • Drug Interactions
    • Patient Counseling
  • Alpha-Receptor Modulators
    • Alpha-2 Adrenergic Agonists
    • Alpha Blockers
  • Acute and Critical Hypertensive Care

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Ischemic Heart Disease Content Review

 
  • Overview
  • Clinical Features
    • Pathophysiology
  • Diagnostic Criteria
  • Non-Pharmaceutical Treatments
  • Pharmaceutical Treatments
    • Antiplatelet Agents
    • Nitroglycerin
    • Antianginal Therapy

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Arrythmias Content Review

 
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    • Pathophysiology
  • Arrythmia Diagnostic Criteria
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    • Abnormal Sinus Rhythm (Arrythmia)
  • Arrythmias
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    • Class IV Antiarrhythmics

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Myocardial Infarction Content Review

 
  • Overview
  • Clinical Features
  • Diagnostic Criteria
  • First-line Pharmaceutical Treatments
    • Fibrinolytics
    • P2Y12 Inhibitors
    • Glycoprotein Receptor Antagonists
  • Second-Line Pharmaceutical Treatments

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Heart Failure Content Review

 
  • Overview
  • Clinical Features
    • Pathophysiology
    • Compensation
  • Diagnostic Criteria
    • Classifications
    • Exacerbating Factors
  • Non-Pharmaceutical Treatments
  • Pharmaceutical Treatments
    • Nitrate/Hydralazine
    • Ace Inhibitors
    • Angiotensin Receptor Blockers
    • Loop Diuretics
    • Aldosterone Receptor Antagonists
    • Adrenergic Receptor Antagonists

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Shock Content Review

 
  • Overview
  • Classifications
    • Pathophysiology
  • Hypovolemic Shock
  • Cardiogenic Shock
  • Anaphylactic Shock
  • Neurogenic Shock
  • Treatments

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Intro to Infectious Diseases Content Review

 
  • Intro to Infectious Diseases
    • Overview

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Intro to Infectious Diseases Content Review

 
  • Identification of Bacteria
    • Shape Classification
    • Gram-Stain Classification
  • Antibiotic Selection
    • Empiric Treatment
    • Data Collection
    • Antibiotic Susceptibility
    • Combination Antibiotic Treatment
  • Common Infections
    • Sites of Infection
  • Treatment Evaluation
  • Antibiotic Use for Surgeries
    • Pre-Operative
    • Intra-Operative
    • Post-Operative
    • Procedure Based Antibiotics
  • Meningitis
    • Overview
    • Clinical Features
    • Pharmaceutical Treatment
  • Peritonitis
    • Primary Peritonitis
    • Secondary Peritonitis

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From students with top scores on the Step 3

The team behind UMock Step 3 with Perfect scores

Perfect scores

Anushka

Yale University

Casey

Neurologist

Mike

Orthopedic Surgery

Julia

Internal medicine (MD)

Each subject review was written by students from Yale University with perfect exam scores. Each subject is condensed into an exceptionally easy-to-learn format with engaging content to more effectively retain concepts.

Anushka

Perfect Score

She graduated magna cum laude from Yale University with a B.S. in Molecular, Cellular, and Developmental Biology. She is currently a fourth-year medical student. She received perfect scores on the MCAT (528/528) and SAT (1600/1600), and has extensive experience for the MCAT, SAT, and AP exams. At Yale, she conducted genetics research and was the recipient of multiple research fellowships. During high school, she was a two-time finalist (top 20) in the U.S. National Chemistry Olympiad and was one of 80 students worlwide selected to attend the prestigious Research Science Institute (RSI) at MIT.

Scores:

  • MCAT: 528 / 528
  • SAT: 1600 / 1600
  • AP Biology: 5 / 5
  • AP Chemistry: 5 / 5
  • AP Physics C: 5 / 5
  • AP Calculus: 5 / 5
  • AP English Language and Composition: 5 / 5
  • AP English Literature and Composition: 5 / 5

Casey

Perfect Score

Casey Vickstrom graduated summa cum laude from Northwestern University in 2014 with a B.A. in Biological Sciences. He is a third-year medical student in the MD/PhD program at the Medical College of Wisconsin, having completed his PhD in Neuroscience in 2020. His research focused on neural circuits and endocannabinoids related to anxiety and depression. He aims to study mechanisms of neurological diseases to identify new therapeutic targets. Casey has extensive tutoring experience for Step 1 and plans to pursue a career in neurology or related specialties. In his free time, he enjoys skiing, soccer, and spending time with family, friends, and his dog.

  • Education:
  • Northwestern University B.A.Honors
  • Medical College of Wisconsin
  • Medical Scientist Training Program (MD/PhD) at present
  • Score:
  • Step 1 - 265/300
  • ACT - 35/36
  • AP Biology - 5/6
  • MCAT - 515/528
  • Biology / Organic chem - 131/136
  • Physical Sciences - 127/136
  • Reading - 127/136

Mike

Perfect Score

  • Education:
  • Georgetown University, B.S.
  • Medical school/Residency:
  • Rutgers Robert Wood Johnson Medical School, M.D.
    Orthopedics Surgery
  • MCAT: 528 / 528
  • USMLE Score:
  • Step 1 - Pass
  • Step 2CK - 245
  • Step 3 - 252
  • SAT Subject Test –
  • Biology (Molecular): 780 / 800
  • Mathematics Level 2: 780 / 800
  • Mathematics Level 1: 750 / 800
  • SAT with Essay: 2330 / 2400
  • Reading: 800 / 800
  • Writing: 770 / 800
  • Math: 760 / 800
  • Chem/Phys: 131 / 136
  • CARS: 131 / 136
  • Bio/Biochem: 130 / 136
  • Psych/Soc: 130 / 136
  • AP Biology: 5 / 5
  • AP Statistics: 5 / 5
  • AP Calculus: 5 / 5
  • Education
  • Georgetown University, B.S.
  • Medical School:
  • Rutgers Robert Wood Johnson Medical School, M.D.
  • Medical school/Residency:
  • Rutgers Robert Wood Johnson Medical School, M.D. Orthopedics Surgery

SAT Subject Test:

  • Biology (Molecular): 780 / 800
  • Mathematics Level 2: 780 / 800
  • Mathematics Level 1: 750 / 800
  • SAT with Essay: 2330 / 2400
  • Reading: 800 / 800
  • Writing: 770 / 800
  • Math: 760 / 800
  • MCAT: 527 / 528
  • Chem/Phys: 131 / 136
  • CARS: 131 / 136
  • Bio/Biochem: 130 / 136
  • Psych/Soc: 130 / 136
  • AP Biology: 5 / 5
  • AP Statistics: 5 / 5
  • AP Calculus BC: 5 / 5

USMLE Score:

  • Step 1 - 276
  • Step 2CK - 280
  • Step 3 - 275

Julia

Perfect Score

Julia is a resident in Internal Medicine. She first developed an interest in helping other students succeed as a high school student, after scoring a 2310 on her own SATs. She went on to earn a Bachelor of Science in Health Care Management and Policy from Georgetown University, Washington, D.C with a concentration in healthcare administration. After earning a 520 and scoring in the 98th percentile on her MCAT exam, Julia continued straight from Georgetown to Sidney Kimmel Medical College at Thomas Jefferson University, in Philadelphia, PA.

  • Score:
  • USMLE® Step 1 - Pass
  • USMLE® Step 2CK - 262/300
  • USMLE® Step 3 - 263/300
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