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COMLEX Level 2 Prep Course Created by Yale Students Who Scored Perfect. Includes Online Course, Qbank, Flashcards, EKG

Complete COMLEX Level 2 Online Course Review Includes

Course

Strengthen your foundation in medical science with our comprehensive course designed for COMLEX Level 1. Covering key topics such as Pathology, Physiology, Pharmacology, and Biochemistry, this course ensures you master the essential concepts for success.

Qbank

Enhance your exam preparation with over 500 questions, complete with detailed explanations. Focus on high-yield topics like Cardiovascular, Endocrine, and Neuroanatomy to maximize your readiness for the exam.

Flashcards

Rapidly reinforce essential concepts with our targeted flashcards. Cover crucial topics such as Microbiology and Immunology for efficient knowledge retention and quick recall.

EKG

Master the core principles of EKG, including its components and interpretation. Develop the skills to identify and diagnose various cardiac conditions by analyzing EKG tracings effectively.

COMLEX Level 2 online course review

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Mastering Core Concepts for COMLEX Level 2  

Building a Strong Foundation in Medical Sciences

COMLEX Level 2 Course Review

In-Depth Review of High-Yield Topics Gain a thorough understanding of Pathology, Physiology, Pharmacology, and Biochemistry to master both normal and abnormal body processes with focused insights.

Effective Learning with Mock Exams Strengthen your exam preparation with comprehensive mock assessments, reinforcing your grasp of the USMLE blueprint and test-taking strategies.

Boost Long-Term Retention Enhance knowledge retention with practice questions, flashcards, and spaced repetition for effective and thorough preparation.

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Complete COMLEX Level 2 online prep course review

COMLEX Level 2 Exam Preparation

Master Core Medical Concepts Build a solid foundation in Pathology, Physiology, Pharmacology, and Biochemistry, integrating basic science with clinical insights for a streamlined review.

Extensive Qbank Practice Sharpen your knowledge with over 3,716 high-yield questions in USMLE format, focusing on essential topics like Cardiovascular, Endocrine, and Neuroanatomy.

Visual and Memory-Boosting Tools Utilize flashcards, diagrams, and charts to reinforce retention and facilitate quick recall of critical medical concepts.

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Includes COMLEX Level 2 Pre-made Flashcards with 501+

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Flashcard 1 of 150

A 4-year-old boy is brought to the emergency department for shortness of breath 

  • She had a cough that started one week ago and progressively worsened. She developed shortness of breath 12 hours ago 
  • Associated symptoms include nasal congestion, low-grade fevers, and decreased appetite 
  • Vital signs are temperature 100.8 F, heart rate 120/min, respiratory rate 28/min, and SpO2 96% on room air 
  • On examination she has inspiratory stridor and a harsh cough. Her breathing is labored, and she has intercostal retractions. The lungs are clear to auscultation bilaterally.
What is the most likely diagnosis and its management?

Diagnosis:

Croup

Management:Inhaled racemic epinephrine, dexamethasone, supportive care

Explanation

Croup (acute laryngotracheobronchitis) is an acute viral syndrome characterized by subglottic and laryngeal edema that result in hoarseness, inspiratory stridor, and barking cough. It is most common in the winter and typically affects children between 6 months and 3 years of age. The majority are related to parainfluenza virus, with the remaining caused by other respiratory viruses (adenovirus, influenza virus, respiratory syncytial virus). Croup is usually preceded by a prodromal phase of acute upper respiratory illness (congestion, rhinorrhea, fever). Patients then develop a barking cough, often described as “seal-like”. This is accompanied by inspiratory stridor, hoarseness, and constitutional signs and symptoms. The severity of croup and associated respiratory distress varies between patients. In severe cases patients may have both inspiratory and expiratory stridor, hypoxia, cyanosis, and respiratory muscle fatigue.

Croup is a clinical diagnosis based on the history and physical examination. Radiographs of the chest characteristically show subglottic narrowing referred to as steeple sign. Management of croup depends on the severity of illness. In mild cases supportive care is the cornerstone of treatment. Corticosteroids (dexamethasone) can be used to reduce airway inflammation. Severe cases that involve stridor and/or respiratory distress should be treated with inhaled racemic epinephrine in addition to corticosteroids and supportive care. Endotracheal intubation is required in a minority of cases due to established or impending airway compromise.

Workup : Clinical diagnosis. Chest radiograph aids in diagnosis.

Management :Inhaled racemic epinephrine, dexamethasone, supportive care

Miscellaneous : Signs of impending respiratory failure include stridor at rest, lethargy, dusky appearance, and altered level of consciousness.

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Flashcard 2 of 150

A 4-month-old male is brought to the emergency department due to fever

  • He has had a fever for the past 3 days with a maximum temperature of 103.2 F 
  • Associated with fussiness, decreased appetite, and decreased urine output
  • The patients mother states that he cries inconsolably during diaper changes 
  • Vital signs are T 102.4 F, HR 140/min, BP 85/50 mm Hg, and RR 30/min
  • On examination the left leg is held flexion, abduction, and internal rotation. Erythema, swelling, and tenderness are present over the left hip.
What is the most likely diagnosis and its management?

Answer:

Diagnosis: Septic arthritis

Management: Joint aspiration and empiric antibiotics

Explanation

Septic arthritis is an infection of the synovial fluid and joint tissues. It is an orthopedic emergency that requires prompt recognition and management. Routes of infection include hematogenous spread of bacteria into the joint space, direct entry through penetrating trauma, or contiguous spread from adjacent osteomyelitis. The most common cause of pediatric septic arthritis in all age groups is staphylococcus aureus. Haemophiles influenza, Escherichia coli, and group B streptococci are other common pathogens. Clinical features include reduced mobility, limping, fever, fussiness, and decreased appetite. Infants with septic arthritis of the hip may have a history of crying during diaper change as this involves manipulation of the lower extremities. The affected leg is held in flexion, abduction, and external rotation as this maximizes the joint space volume and reduces pain. Joint tenderness, swelling, erythema, and warmth are common examination findings. If there is suspicion for septic arthritis, the affected joint should be aspirated. Synovial fluid WBC count greater than 50,000/ml suggests septic arthritis. The fluid should also be sent for culture. Imaging has a limited role on the diagnosis of septic arthritis however should be used to rule out other causes of joint pain. Septic arthritis should be managed in conjunction with orthopedic and infectious disease specialists when possible. Antibiotics and joint drainage are the cornerstones of management. Antibiotic therapy should be started as soon as possible. Initial management can be guided by gram stain, age, and risk factors. Children < 3 months should initially be treated with an antistaphylococcal agent (oxacillin, vancomycin) plus ceftazidime, cefotaxime, or cefepime. Children > 3 months should be treated with an antistaphylococcal agent (vancomycin, clindamycin). Septic arthritis of the hip often requires arthrotomy and open drainage to avoid permanent joint damage.

Workup:

CBC, CRP, ESR, synovial fluid studies

Management:

Joint drainage (aspiration, arthrotomy) and empiric antibiotics

Miscellaneous

A delay in the diagnosis and management of septic arthritis of the hip can lead to long term complications such as femoral neck deformity, limb-length discrepancy, osteonecrosis, femoral head destruction, and growth disturbance.

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Flashcard 3 of 150

A 13-year-old male is brought to the emergency department due to abdominal pain

  • The pain has been gradually worsening over the past day. It is described as epigastric, constant, and non-radiating 
  • Associated with multiple episodes of non-bloody, non-bilious vomiting 
  • He was involved in a bicycle accident where he fell forward onto the handlebars three days ago
  • Examination is remarkable for abdominal distension
  • CT scan with contrast reveals gastric distension and narrowing of the second portion of the duodenum
What is the most likely diagnosis and its management?

Answer:

Diagnosis: duodenal hematoma

Management: NG tube, NPO, parenteral nutrition

Explanation

Duodenal hematoma is an uncommon complication of blunt abdominal trauma that most commonly seen in children. It is classically associated with a handlebar injury but can also occur in the setting of child abuse, motor vehicle collisions, falls, and sports related injuries. The abdominal organs in pediatric patients are more vulnerable to injury due to thinner abdominal muscles, more compliant ribs, and horizontal orientation of the diaphragm leading to increased organ exposure. Duodenal hematoma usually presents in the days following an abdominal injury. Symptoms include vomiting, abdominal pain, abdominal distension, and anorexia. External signs of trauma are not always evident. Imaging is necessary for a definitive diagnosis. It can be diagnosed with upper GI series or a contrast enhanced CT scan. Water soluble contrast should be used if perforation is suspected. Duodenal hematomas can be managed conservatively with nasogastric tube placement and parenteral nutrition. Ultrasonography can be used to follow a resolving hematoma. If symptoms do not resolve operative management may be necessary.

Workup:

Upper GI series or contrast enhances CT

Management:

Conservative in majority of cases with nasogastric tube placement and parenteral nutrition.

Miscellaneous

Injury to surrounding organs (most commonly the liver) is common in patients with duodenal hematoma.

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Flashcard 4 of 150

A 67-year-old male presents to the emergency department due to genital pain

  • The pain started 2 days ago in the scrotum and perineal region. He states that it was initially mild but now rates it 10/10 
  • Associated symptoms include fever, anorexia, and malaise for the past 3 days 
  • His past medical history includes type II diabetes, hypertension, and hyperlipidemia. He recently began having symptoms of urinary obstruction and underwent a prostate biopsy 5 days ago 
  • Vital signs are temperature 102.5 F, heart rate 110/min, blood pressure 150/70 mmHg, and respiratory rate 20/min 
  • Examination reveals dusky appearing skin over the perineum and scrotum along with edema and exquisite tenderness What is the most likely diagnosis and its management?
What is the most likely diagnosis and its management?

Answer:

Diagnosis: Fournier’s gangrene

Management: Broad spectrum antibiotics and surgical debridement

Explanation

Fournier’s gangrene is a rapidly progressive necrotizing infection of the perineum and genital region. As with other necrotizing infections, the infection spreads along the superficial and deep fascial planes. The overlying skin is usually spared, and the extent of infection is often difficult to appreciate. Fournier’s gangrene is a polymicrobial infection. The most common organism isolated are streptococcal species, staphylococcal species, anaerobic organisms, and Enterobacteriaceae. There are various routes of entry for infection including the urogenital tract, skin of the genitalia, and anorectum. Common causes of Fournier’s gangrene are perianal infections, anal fistula, urethral injury, urethral manipulation, prostate biopsy, urinary tract infections, epididymitis, scrotal injury, orchitis, and hidradenitis. It is more common in patients with impaired immunity due to diabetes, alcoholism, old age, HIV infection, malignant, immunosuppressive therapy, or alcoholism.

The presentation of Fournier’s gangrene is variable and can develop insidiously or rapidly. A prodromal phase consisting of fever and lethargy may occur up to a week prior to the onset of pain. The pain is typically severe and associated with edema of the overlying skin. In the initial stages the pain is often out of proportion to the physical exam findings. Eventually erythema of the skin develops, followed by subcutaneous crepitations and eventually gangrene with purulent drainage from wounds in the perineum and/or genitalia. Constitutional symptoms including fever, loss of appetite, malaise, and nausea are often present.

The diagnosis is established clinically based on the history and examination. Laboratory studies and Imaging such as computed tomography (CT) or ultrasonography should be obtained to evaluate the extent of infection. Fournier’s gangrene is a urologic emergency associated with a high mortality rate if not treated rapidly and appropriately. After initial stabilization, the cornerstones of therapy are broad spectrum antibiotic therapy and urgent surgical debridement of the necrotic tissue. Initial antibiotics should cover all of the potential causative organisms. Common antibiotic choices are ampicillin-sulbactam, piperacillin-tazobactam, or ticarcillin-clavulanate in addition to clindamycin and vancomycin.

Workup:

Clinical diagnosis. Imaging (CT, US) to evaluate extent of infection.

Management:

Broad spectrum antibiotics and surgical debridement

Miscellaneous

SGLT-2 inhibitors increase the risk of Fournier’s gangrene in diabetic patients.

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Flashcard 5 of 150

A 26-year-old male presents to the clinic due to abdominal pain

  • He complains of intermittent right lower quadrant pain. He was evaluated in the emergency department three times in the last 2 months. Laboratory tests and a CT of the abdomen were negative
  • He is concerned that he has colon cancer. He states that he spends time researching his symptoms on the internet daily. He missed several days of work due to appointments with various physicians
  • He was evaluated by neurology last month due to fasciculations. He is worried that he is having the initial manifestations of ALS
  • Vital signs are within normal limits, and physical examination is unremarkable
What is the most likely diagnosis and its management?

Answer:

Diagnosis: Illness anxiety disorder

Management: Cognitive behavioral therapy

Explanation

Illness anxiety disorder (IAD), formerly known as hypochondriasis, is a psychiatric condition characterized by excessive fear of or preoccupation with having or developing a serious medical condition. The etiology of IAD is not known. It is associated with underlying anxiety disorders such as generalized anxiety disorder and panic disorder. Patients may have a personal or family history of severe illness during childhood.

IAD presents with severe, often disabling preoccupation with having a serious medical disorder despite a normal workup, few or mild somatic symptoms, and reassurance. Patients with IAD often seek advice from several physicians as they believe that their serious condition was missed. Common and benign symptoms such as occasional fasciculations or stomach rumbling are interpreted as signs of a serious medical condition.

The DSM-V criteria for illness anxiety disorder are as follows:

  • Excessive worry about having or developing a serious illness
  • Absence of somatic symptoms. If present, the symptoms are mild
  • Excessive concern and anxiety regarding health-related issues
  • Disproportionate and redundant health related behaviors 
  • Symptoms have been present for at least 6 months 
  • Symptoms are not better explained by another psychiatric condition

Cognitive behavioral therapy is first-line treatment for IAD. It involves behavioral modifications and education about normal somatic sensations. Pharmacologic therapy is second line. selective serotonin reuptake inhibitors (SSRIs) and serotonin-norepinephrine reuptake inhibitors (SNRIs) are the preferred initial agents.

Workup:

Clinical diagnosis

Management:

Cognitive behavioral therapy

Miscellaneous

Unnecessary studies and procedures should be avoided in patients with illness anxiety disorder (IAD).

High-Yield Flashcards by Subjects and Topics:

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Designed with concise and focused facts, the premade flashcards enable quick learning and easy retention, making them an indispensable tool in your MCAT preparation.

Complete COMLEX Level 2 Online Course Review
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Pathology 45% - 52%

 

Pathology makes up the majority of content covered on the exam, representing 44-52% of questions. The UMock USMLE® Step 1 prep course presents concise, high-yield content covering pathophysiologic, morphology, and pathogenesis, focused on the core knowledge of disease mechanisms and clinical aspects you need to know for the exam.

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Physiology 25% - 35%

 

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Pharmacology Content Review 15% - 22%

 

Pharmacology accounts for roughly 15-22% of questions covered on the exam. The UMock USMLE® Step 1 prep course presents a comprehensive overview in a concise chapter-by-chapter format to help you gain an understanding of the principles in pharmacology and their classification, pharmacodynamic and pharmacokinetic processes, the mechanism of the action of drugs, usage, and their adverse effects.

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Biochemistry Content Review 14% - 22%

 

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Microbiology Content Review 10% - 15%

 

Microbiology represents approximately 10-15% of exam questions, requiring memorization and applying concepts. The course includes high quality micro classification charts and slides for Gram (+) and Gram (-) rods to help you visualize and understand the application of microbiology in basic medical science.

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Immunology Content Review 6% - 11%

 

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Hematology and Oncology Content Review 7% - 11%

 

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Cardiovascular System Content Review 5% - 9%

 

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Respiratory System Content Review 9% - 13%

 

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Gastrointestinal Tract Content Review 5% - 9%

 

The gastrointestinal system represents roughly 5-9% of test items. The UMock USMLE® Step 1 prep course gives you a comprehensive and concise review of high-yield material to help you memorize, understand, and apply information to clinical scenarios pertaining to concepts of digestion and how one factor is affected by another, malabsorption syndromes, as well as the histopathology type of each location, and where the pharmacotherapies take action.

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Renal and Urinary System Content Review 9% - 13%

 

The renal and urinary system make up questions heavily weighted on physiology-focused concepts. The UMock USMLE® Step 1 prep course provides a high-yield review of essential concepts in a clear and concise format to help you understand and apply the connection between renal tubule physiology and the diuretics that work on the tubule, as well as applying concepts in nephritic and nephrotic syndromes to clinical scenarios.

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Male Reproductive System Content Review 9% - 13%

 

In the reproductive system, the UMock USMLE® Step 1 prep course covers the male and female reproductive system as well as pregnancy, childbirth, and the puerperium. The course provides high-yield topics concentrated on clear and concise explanations to help you understand and apply concepts to clinical scenarios associated with the hormonal pathways of the male and female reproductive systems.

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Female Reproductive System Content Review 9% - 13%

 

In the reproductive system, the UMock USMLE® Step 1 prep course covers the male and female reproductive system as well as pregnancy, childbirth, and the puerperium. The course provides high-yield topics concentrated on clear and concise explanations to help you understand and apply concepts to clinical scenarios associated with the hormonal pathways of the male and female reproductive systems.

The course integrates concepts with high quality microscopic views and diagnostic images to help you improve recall of normal and abnormal processes in disease and apply it to clinical scenarios like you’ll see on the exam.

  • Ovaries
  • Breast
  • Vulva & Vagina
  • Uterine Cervix
  • Uterine Corpus
  • Fallopian Tubes
  • Disorders of Pregnancy
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Endocrine System Content Review 9% - 13%

 

The UMock USMLE® Step 1 prep course combines concise high yield topics with detailed diagrams covering normal and abnormal processes of endocrine-specific pathologies and physiologies. The course helps you gain a clear understanding of how to apply concepts to clinical scenarios for keeping hormone levels in balance, diagnostic testing, treatment, and management.

The course includes descriptive illustrations, microscopic views, images, and graphs highlighting heavily test exam content to help you gain a full understanding of applying concepts for normal and abnormal processes of the endocrine system.

  • Endocrine Pancreas
  • Endocrine of Pituitary
  • Endocrine of Thyroid Gland
  • Endocrine of Adrenal Glands
  • Endocrine of Parathyroid Glands
  • Multiple Endocrine neoplasia (MEN) Syndrome
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Dermatology Content Review 6% - 10%

 

In Dermatology, the UMock USMLE® Step 1 prep course gives you concise, high yield topics to help you understand how to apply basic concepts to clinical scenarios in comparing similar pathologies based on the morphology and distribution of conditions.

Every topic is covered for both normal and abnormal body-system processes with high quality microscopic views and gross images to help you visually understand the application of medicine specific to diseases in skin and subcutaneous tissue.

  • Pruritus
  • Urticaria
  • Common Rashes
  • Infestations
  • Bites & Stings
  • Hair Disorders
  • Common Neoplasms
  • Acneiform Eruptions
  • Common Skin Infections
  • Cuts, Scrapes, & Burns
  • Foot and Leg Ulcers
  • Nail Disorders
  • Disorders of Mucous Membranes
  • Autoimmune Blistering Diseases
  • Therapeutic Principles in Dermatology
  • Dermatologic Urgencies and Emergencies
  • Cutaneous Manifestations of Internal Disease
  • Dermatologic Problems of Special Populations
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Nervous System Content Review 4% to 7%

 

Exam items covering the nervous system represent about 4-7% of test questions. The UMock Step 1 Prep Course clearly explains gross anatomy and neuroanatomy and normal and abnormal processes from this area, including

  • Embryonic development
  • Fetal maturation
  • Perinatal changes
  • Neural tube derivatives
  • Cerebral ventricles
  • Neural crest derivatives
  • Organ structure & function
  • Cell & tissue structure & function
  • Repair
  • Regeneration
  • Changes associated with life stages
  • Infectious
  • Immunologic
  • Inflammatory disorders
  • Neoplasms
  • Cerebrovascular disease
  • Disorders related to spinal cord
  • Spine
  • Spinal nerve roots
  • Cranial & peripheral nerve disorders
  • Neurologic pain syndromes
  • Degenerative disorders
  • Global cerebral dysfunction
  • Neuromuscular
  • Metabolic disorders
  • Paroxysmal disorders
  • Sleep disorders
  • Traumatic & mechanical disorders
  • Increased intracranial pressure
  • Congenital disorders
  • Disorders of the eye & eyelid
  • Disorders of the ear
  • Movement disorders
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Rheumatology and Musculoskeletal Content Review 6% - 10%

 

The UMock USMLE® Step 1 prep course provides the most valuable exam information with a complete and concise review of high-yield topics to help you quickly understand and apply knowledge to clinical scenarios covering the diagnosis of joint pathologies, and anatomical paths of distal branches and the muscles that they innervate.

The course features detailed tables and high quality radiologic and gross images to help you conceptualize the application of medicine for normal and abnormal body system processes and pathologies in rheumatology and the musculoskeletal system.

  • Diseases of Skeletal Muscle
  • Diseases of Bone
  • Diseases of Joints
  • Soft-Tissue Tumors
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Behavioral Science Content Review 8% to 13%

 

Behavioral science accounts for roughly 8-13% of exam questions. The UMock USMLE® Step 1 prep course helps you clarify difficult concepts in the mind-body relationship, and understand how to apply DSM-IV and DSM-5 diagnostic criteria in the manifestations of psychological disorders to various clinical scenarios with a high-yield, concise review of concepts covering every topic for normal and abnormal processes.

The course includes descriptive diagrams, tables, and images to provide a concentrated review of material to help you fully understand the application of behavioral science to clinical medicine.

  • Sexuality
  • Learning Theory
  • Beginning of Life
  • Anxiety Disorders
  • Aggression & Abuse
  • Psychosomatic Medicine
  • Somatic Symptom Disorders
  • Obsessive-Compulsive Disorders
  • Trauma & Stressor-Related Disorders
  • Substance-related Disorders
  • Sleep & Sleep-wake Disorders
  • Psychological Therapies
  • Family, Culture, & Illness
  • Psychiatrics Disorders in Children
  • Aging, Death, & Bereavement
  • School Age, Adolescence, & Adulthood
  • Psychoanalytic Theory & Defense Mechanisms
  • Depressive Disorders & Bipolar Disorders
  • Schizophrenia Spectrum & other Psychotic Disorders
  • Clinical Assessment of Patients with Behavioral Symptoms
  • Biological Assessment of Patients with Psychiatric Symptoms
  • Neurocognitive, Personality, Dissociative & Eating Disorders
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Embryology Content Review 11% - 15%

 

In Embryology, the UMock USMLE® Step 1 prep course presents high-yield content in a concise format that helps you understand and quickly recall concepts in human development and congenital malformations, and apply the connection between embryological knowledge and clinical medicine. The course further clarifies key facts and concepts to help you maximize comprehension and visual understanding in applying concepts with high quality diagnostic, radiographic, and clinical images.

  • Skeletal System
  • Muscular System
  • Upper Limb
  • Lower Limb
  • Body Cavities
  • Pregnancy
  • Teratology
  • Head & Neck
  • Prefertilization Events
  • Human Development - Week 1
  • Human Development - Week 2
  • Embryonic Period
  • Cardiovascular System
  • Placenta & Amniotic Fluid
  • Embryology of the Ear
  • Embryology of the Eye
  • Embryology of the Nervous
  • Embryology of the Digestive
  • Embryology of the Respiratory
  • Urinary System
  • Female Reproductive System
  • Male Reproductive System
  • Integumentary System
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Women’s Health and Pregnancy Content Review 3% to 5%

 

The musculoskeletal system accounts for roughly 3-5% of the exam. Learn everything covered on this section of the exam for normal and abnormal process with the UMock Step 1 Prep Course:

  • Tendon
  • Repair
  • Joints
  • Usage
  • Muscles
  • Cartilage
  • Arthritis
  • Infectious
  • Regeneration
  • Blood supply
  • Gross anatomy
  • Neoplasms
  • Embryonic development
  • Organ structure & function
  • Changes associated with life stages
  • Cell & tissue structure & function
  • Ligaments & fascia
  • Traumatic & mechanical disorders
  • Mechanism of the action of drugs
  • Fetal maturation & perinatal changes
  • Inflammatory & immunologic disorders
  • Adverse effects on the musculoskeletal system
  • Degenerative & metabolic disorders of bone
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Histology Content Review 8% to 13%

 

Histology makes up about 8-13% of questions on the exam. The UMock USMLE® Step 1 prep course offers a high-yield review condensed concepts format to help you better understand the relationship between cell structure and function to biological tissues, and effectively apply concepts to clinical scenarios on the exam. The course includes high quality micrographs, illustrations, and tables to further enhance your ability to quickly recall concepts and how they apply in clinical practice.

  • Cell Histology
  • Extracellular Matrix
  • Epithelia & Glands
  • Connective Tissue
  • Blood & Hemopoiesis
  • Histology Cartilage & Bone
  • Histology Muscle
  • Nervous Tissue
  • Circulatory System
  • Histology of Lymphoid
  • Histology of Endocrine
  • Histology of Skin
  • Histology of Respiratory
  • Histology of Digestive
  • Urinary Glands
  • Female Reproductive
  • Male Reproductive
  • Special Senses
  • Cavity and Alimentary Tract
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Anatomy Content Review 11% to 15%

 

In Anatomy, the UMock USMLE® Step 1 prep course presents the most important high-yield facts you need to memorize for the exam, and helps you understand and apply clinical correlations of the structure and organization of the body to clinical scenarios such as fractures, trauma, and injuries. The course is illustrated with high quality descriptive images of anatomic relationships to further enhance your ability to apply knowledge to concepts.

  • Perineum
  • Vertebral Column
  • Spinal Cord & Spinal Nerves
  • Autonomic Nervous System
  • Lymphatic System
  • Chest Wall
  • Anatomy of the Heart
  • Abdominal Wall
  • Kidney, Ureter, Bladder, & Urethra
  • Suprarenal Glands
  • Abdominal Vasculature
  • Abdominal Viscera
  • Anatomy of the Pelvis
  • Spleen
  • Female Reproductive
  • Male Reproductive
  • Anatomy of the Upper Limb
  • Anatomy of the Lower Limb
  • Anatomy of the Head
  • Anatomy of the Neck
  • Anatomy of the Eye
  • Anatomy of the Ear
  • Pleura, Tracheobronchial Tree, & Lungs
  • Sigmoid Colon, Rectum, & Anal Canal
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Neuroanatomy Content Review 9% to 13%

 

In Neuroanatomy, the UMock USMLE® Step 1 prep course provides high-yield concepts in a clear and concise presentation to help you thoroughly understand and apply concepts in clinical scenarios covering different pathways and tracts, patterns, distribution territories, and the results of lesions.

In Neurology, the UMock USMLE® Step 1 prep course offers a clear and concise approach to helping you understand and apply concepts to clinical scenarios with high yield concepts covering the relationship between nerves and neurotransmission, and neurologic disease

The course features high quality illustrations, detailed tables, and radiologic images for both normal and abnormal processes to help you better understand how to apply concepts for diagnosis, treatment and management of neurologic diseases.

  • Cerebellum
  • Neurohistology
  • Cranial nerves
  • Auditory System
  • Vestibular System
  • Cerebral Cortex
  • Visual System
  • Gross Anatomy of the Brain
  • Tracts of the Trigeminal system
  • Meninges & Cerebrospinal Fluid
  • Development of the Nervous System
  • Olfactory, Gustatory, & Limbic
  • Autonomous Nervous System
  • Neurotransmitters & Pathways
  • Diencephalon: Thalamus & Hypothalamus
  • Blood supply of the Central Nervous System
  • Tracts & Lesions of the Spinal Cord & Brainstem
  • Tracts & Lesions of the Spinal Cord & Brainstem
  • Basal Nuclei & the Extrapyramidal Motor System
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Legal and Ethics Content Review 6% to 10%

 

The UMock USMLE® Step 1 prep course gives you a clearly explained review of high-yield topics to help you understand how to apply, and make a decision in clinical scenarios involving calculated risks, promoting the patients’ best interest, and respecting the patient’s decisions about their own health. Topics from the course include:

  • Minors
  • Abortion
  • Refusing Care
  • Confidentiality
  • Informed Consent
  • Abuse & Neglect
  • Reportable Diseases
  • Ethical Principles
  • Healthcare Legislation
  • Capacity & Competency
  • Physician Assisted Suicide
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Biostatistics and Epidemiology Content Review 4% to 6%

 

Biostatistics and Epidemiology covers roughly 4-6% of exam questions. The UMock USMLE® Step 1 prep course clarifies difficult concepts with a concise review of high-yield concepts. The course eliminates excessive detail to help you memorize and understand how to efficiently identify and extract the most important information, and apply your knowledge to concepts and formulas. The course includes high quality graphs and tables that clearly illustrate the most important and heavily tested concepts you need to know how to apply for the exam, including:

  • Research Methods
  • Hypothesis Testing
  • Descriptive Statistics
  • Differential Statistics
  • Assessing the Evidence
  • Correlational & Predictive Techniques
  • Statistics in Medical Decision Making
  • Epidemiology & Population Health
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Biostatistics and Epidemiology Content Review 4% to 6%

 

Biostatistics and Epidemiology covers roughly 4-6% of exam questions. The UMock USMLE® Step 1 prep course clarifies difficult concepts with a concise review of high-yield concepts. The course eliminates excessive detail to help you memorize and understand how to efficiently identify and extract the most important information, and apply your knowledge to concepts and formulas. The course includes high quality graphs and tables that clearly illustrate the most important and heavily tested concepts you need to know how to apply for the exam, including:

  • Research Methods
  • Hypothesis Testing
  • Descriptive Statistics
  • Differential Statistics
  • Assessing the Evidence
  • Correlational & Predictive Techniques
  • Statistics in Medical Decision Making
  • Epidemiology & Population Health
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UMock COMLEX Level 2 Content

Biochemistry Cardiology Endocrinology Gastrointestinal General pathalogy Genetics Hematology and Oncology Immunology Integumentary
Microbiology Musculoskeletal Neurology Pharmacology Psychiatry Public health The Pulmonary System Renal Reproduction
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Biochemistry course review topics in UMock

 
  • Nucleic acids
  • Purine synthesis
  • Antimetabolites
  • DNA structure
  • DNA and RNA comparison
  • Chromatin structure
  • Chromatin regulation
  • Central dogma
  • DNA replication
  • DNA damage
  • DNA repair
  • LAC operon
  • RNA
  • Spliceosome
  • RNA translation
  • Amino acids
  • Protein structure
  • Cell membrane
  • Cell membrane proteins
  • Cellular transport
  • Exocytosis and endocytosis
  • Endocytosis
  • Ubiquitin
  • Cellular respiration
  • Carbohydrates
  • Glycolysis
  • Pyruvate
  • Glycogen
  • Glycogen breakdown
  • Glycogen storage diseases
  • Kreb’s cycle
  • Amino acid catabolism
  • Fatty acid oxidation
  • Fatty acid metabolism
  • Mitochondrial shuttles
  • Mitochondria
  • Mitochondrial genome
  • Electron transport chain
  • Cell respiration
  • Urea cycle
  • Inborn errors of urea cycle
  • Cori cycle
  • Amino acid metabolism
  • Phenylketonuria
  • Tyrosine catabolism
  • Catecholamine synthesis
  • Cystinuria
  • Alkaptonuria
  • Vitamin B1
  • Vitamin B2
  • Vitamin B3
  • Vitamin B4
  • Vitamin B5
  • Vitamin B6
  • Vitamin B7
  • Vitamin B12
  • Vitamin C
  • Vitamin D
  • Vitamin E
  • Vitamin K
  • Magnesium
  • Copper metabolism
  • Micronutrients

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Cardiology course review topics in UMock

 
  • Introduction to cardiovascular system
  • Cardiac anatomy
  • Cardiac physiology
  • Cardiovascular pathophysiology
  • Cardiovascular pharmacology

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Endocrinology course review topics in UMock Content Review

 
  • Introduction to endocrinology
  • The thyroid gland
  • The hypothalamus and pituitary
  • The adrenal glands
  • The parathyroid glands
  • The endocrine pancreas

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Gastrointestinal course review topics in UMock Content Review

 
  • Introduction to the gastrointestinal system
  • Gastrointestinal anatomy
  • Gastrointestinal physiology
  • Gastrointestinal pathophysiology
  • Gastrointestinal pharmacology

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General pathalogy course review topics in UMock Content Review

 
  • Tumor
  • Tumorigenesis
  • Cancer associations
  • Cancer genes
  • Carcinogens
  • Carcinogens
  • Tumor grade and stage
  • Tissue and serum markers
  • Oncogenic pathogens
  • Cancer manifestations
  • Histological markers
  • Paraneoplastic syndromes
  • Common tumors
  • Cancer risk factors

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Genetics course review topics in UMock Content Review

 
  • Cell division
  • Terminology
  • Cytogenetics
  • Population genetics
  • Mutation detection
  • Genetic disorders by chromosome
  • Prenatal counseling & diagnostics
  • Chromosome deletion
  • Nondisjunction
  • Down syndrome
  • Trisomies
  • Sex chromosomes
  • Mutation subtypes
  • Genetic inheritance
  • Enzyme deficiency disorders
  • Cystic fibrosis
  • Genetic inheritance
  • Muscular dystrophies
  • Mitochondrial inheritance
  • Multifactorial inheritance
  • Triplet repeat disorders
  • Imprinting
  • Chromosome abnormalities
  • Molecular biology techniques
  • Genetic mapping and linkage
  • Gene cloning
  • Reverse genetics

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Hematology and Oncology course review topics in UMock Content Review

 
  • Embryology
  • Anatomy
  • Physiology
  • Anatomy
  • Brachial plexus
  • Pathology
  • Birth related injuries
  • Childhood disorders
  • Anatomy
  • Collagen disorders
  • Common fractures
  • Shoulder dislocation
  • Fracture repair
  • Neck anatomy
  • Neck triangles
  • Blood supply
  • Shoulder anatomy
  • Upper arm anatomy
  • Forearm anatomy
  • Hand anatomy
  • Carpal tunnel syndrome
  • Wrist pathology
  • Hand deformities
  • Knee anatomy
  • Knee pathology
  • Hip joint
  • Vascular supply
  • Hip and thigh anatomy
  • Lower leg anatomy
  • Venous system
  • Venous system
  • Lower limp
  • Thigh anatomy
  • Femoral triangle
  • Foot anatomy
  • Back pain
  • Disk herniation
  • Refereed pain
  • Vertebral disorders

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Immunology course review topics in UMock Content Review

 
  • Cellular injury
  • Lymphoid structures
  • Cellular components
  • Cellular pathways
  • Humoral mediators
  • Inflammatory response
  • Immune cells
  • Immune response
  • Humoral immunity
  • Immune dysfunction

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Integumentary course review topics in UMock Content Review

 
  • Skin anatomy
  • Dermatological terminology
  • Common skin disorders
  • Skin tumors
  • Skin ulcers
  • Drug-induced cutaneous reactions
  • Cutaneous infections
  • Cutaneous burn injuries

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Microbiology course review topics in UMock Content Review

 
  • Staining techniques
  • Microscopy techniques
  • Bacteria
  • Bacterial structure
  • Culture techniques
  • Toxins
  • Bacterial characteristics
  • Staphylococcus
  • Streptococcus
  • Bacillus
  • Listeria
  • Clostridium
  • Rickettsial disease
  • Ehrlichiosis

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Musculoskeletal course review topics in UMock Content Review

 
  • Embryology
  • Anatomy
  • Physiology
  • Anatomy
  • Brachial plexus
  • Pathology
  • Birth related injuries
  • Childhood disorders
  • Anatomy
  • Collagen disorders
  • Common fractures
  • Shoulder dislocation
  • Fracture repair
  • Neck anatomy
  • Neck triangles
  • Blood supply
  • Shoulder anatomy
  • Upper arm anatomy
  • Forearm anatomy
  • Hand anatomy
  • Carpal tunnel syndrome
  • Wrist pathology
  • Hand deformities
  • Knee anatomy
  • Knee pathology
  • Hip joint
  • Vascular supply
  • Hip and thigh anatomy
  • Lower leg anatomy
  • Venous system
  • Lower limp
  • Thigh anatomy
  • Foot anatomy
  • Back pain
  • Disk herniation
  • Refereed pain
  • Vertebral disorders
  • Compartment syndrome
  • Common pathologies
  • Bone pathology
  • Benign bone tumors
  • Malignant bone tumors
  • Overview
  • Elastic fiber disorders
  • Ehlers-danlos disorder
  • Rheumatoid arthritis
  • Osteoarthritis
  • Psoriatic arthritis
  • Gout
  • Pseudogout
  • Gout and pseudogout
  • Ana patterns
  • Lupus
  • Neonatal lupus
  • Lupus nephritis
  • Antiphospholipid syndrome
  • Scleroderma
  • Giant cell arteritis
  • Sjögren syndrome
  • Erythema nodosum
  • Vasculitis
  • Fibromyalgia
  • Pharmacology
  • Femoral triangle

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Neurology course review topics in UMock Content Review

 
  • Embryology
  • Neurophysiology
  • Neuroanatomy
  • Neuropathology
  • Guide to brainstem lesions
  • Brainstem vascular syndromes
  • Brainstem vascular syndromes
  • Cranial nerves
  • Cranial nerves
  • Autonomic nervous system
  • Sympathetic innervation
  • Parasympathetic innervation
  • Reflexes
  • Primitive reflexes
  • Sympathetic innervation
  • Spinal lesions
  • Spinal tracts
  • Spinal cord syndromes
  • Cns tumors
  • Sleep physiology
  • Headaches
  • Seizure disorders
  • Seizures
  • Olfactory nerve
  • Gustatory system
  • Vestibular system
  • Ophthalmology
  • Pupil reflex
  • Eye-blink reflex
  • Ophthalmology
  • Cns pharmacology
  • Cranial nerve nuclei

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Pharmacology course review topics in UMock Content Review

 
  • Reaction kinetics
  • Pharmacokinetics
  • Cytochrome p450
  • The adrenal glands
  • Acid-base chemistry
  • Efficacy and potency
  • Enzyme inhibitors
  • Allosteric modulators
  • Receptor agonist
  • G-protein family
  • G-protein -coupled receptors
  • Second messenger systems
  • Ligand-gated ion channels
  • Ion channels
  • Sympathetic system
  • Sympathomimetics
  • Sympatholytics
  • Adrenergic agents
  • Adrenergic response
  • Parasympathetic system
  • Parasympathetic system
  • Cholinergic agonists
  • Parasympathetic system
  • Drugs affecting pupil size
  • Micturition
  • Drug side effects
  • Acetaminophen
  • Drug overdose/poisoning
  • Antidotes
  • Pharmacologic suffixes
  • Teratogenic drugs

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Psychiatry course review topics in UMock Content Review

 
  • Psychology
  • Childhood disorders
  • Mood disorders
  • Postpartum mood disorders
  • Dissociative disorders
  • Delirium and dementia
  • Psychotic disorders
  • Malingering disorders
  • Anxiety disorders
  • Personality disorders
  • Somatoform disorders
  • Sleep disorders
  • Gender and sexual disorders
  • Eating disorders
  • Psychiatric emergencies
  • Substance use disorders

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Public health course review topics in UMock Content Review

 
  • Epidemiology
  • Biostatistics
  • Ethics
  • Communication skills
  • Healthcare delivery
  • Quality and safety

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The Pulmonary System course review topics in UMock Content Review

 
  • Introduction to the pulmonary system
  • Pulmonary anatomy
  • Pulmonary physiology
  • Respiratory pathophysiology
  • Pulmonary pharmacology

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Renal course review topics in UMock Content Review

 
  • Kidney embryology
  • Kidney macroscopic anatomy
  • Lower urinary system
  • Fluids
  • Electrolytes
  • Kidney microscopic anatomy
  • Kidney physiology
  • Cystic disorders
  • Nephrotic disorders
  • Nephritic disorders
  • Renal failure
  • Urinary casts and stones
  • Urinary tract infections
  • Urinary system tumors

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Reproduction course review topics in UMock Content Review

 
  • Embryology-reproductive system
  • Embryology-male reproduction
  • Embryology-male reproductive system
  • Anatomy-male reproductive system
  • Pathology-male reproductive organs
  • Anatomy-reproductive system
  • Physiology-hypothalamic-pituitary axis
  • Physiology-menstrual cycle
  • Pathology-breast
  • Pathology-vulva
  • Pathology-vagina
  • Pathology-cervix
  • Physiology-embryonic development
  • Physiology-placentation
  • Physiology-placental hormones
  • Physiology-placental steroids
  • Pathology- female reproductive organs
  • Pathology-sex development
  • Pathology-puberty
  • Pathology-postpartum complications
  • Pathology-uterus
  • Pathology-ovaries
  • Pathology-ovarian tumors
  • Pathology-ovaries
  • Physiology-maternal adaptations
  • Physiology-lactation
  • Physiology-pregnancy and infection
  • Physiology -sexual development
  • Physiology–pubertal growth
  • Physiology–sexual development
  • Pathology-gamete interaction
  • Pathology-implantation
  • Pathology-placenta
  • Pathology-fetal blood vessels
  • Pathology-fetal blood vessels
  • Physiology-fertilization
  • Pathology-maternal serum screening
  • Pathology-pregnancy hypertension
  • Pathology-fetal growth
  • Pathology-teratogens
  • Pathology-sex chromosomes
  • Pathology-fallopian tubes
  • Pharmacology-hormone modulators
  • Pharmacology-contraception
  • Physiology-germ cells
  • Physiology-gametogenesis
  • Physiology-gamete interaction
  • Physiology-implantation

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UMock equips medical students with foundational knowledge and basic science closely aligned with the exam specifications.

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This course offers a comprehensive review of the most frequently tested topics from the current exam outline.

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UMock brings outstanding exam performance strategies right to your fingertips, with content created by top medical students from leading universities.

Thorough Subject Review for COMLEX Level 2

Each chapter is meticulously reviewed to provide you with the most accurate, up-to-date, and high-yield content available.

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Streamline your learning process by simplifying how you understand, memorize, and apply complex concepts.

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From students with top scores on the COMLEX Level 2

The team behind UMock COMLEX Level 2 with Perfect scores

Perfect scores

Anushka

Anushka

Yale University

Anjali

Anjali

Yale University

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Casey

Neurologist

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Mike

Orthopedic Surgery

Each subject review was written by students from Yale University with perfect exam scores. Each subject is condensed into an exceptionally easy-to-learn format with engaging content to more effectively retain concepts.

Anushka

Perfect Score

She graduated magna cum laude from Yale University with a B.S. in Molecular, Cellular, and Developmental Biology. She is currently a fourth-year medical student. She received perfect scores on the MCAT (528/528) and SAT (1600/1600), and has extensive experience for the MCAT, SAT, and AP exams. At Yale, she conducted genetics research and was the recipient of multiple research fellowships. During high school, she was a two-time finalist (top 20) in the U.S. National Chemistry Olympiad and was one of 80 students worlwide selected to attend the prestigious Research Science Institute (RSI) at MIT.

Scores:

  • MCAT: 528 / 528
  • SAT: 1600 / 1600
  • AP Biology: 5 / 5
  • AP Chemistry: 5 / 5
  • AP Physics C: 5 / 5
  • AP Calculus: 5 / 5
  • AP English Language and Composition: 5 / 5
  • AP English Literature and Composition: 5 / 5

Anjali

Perfect Score

She graduated magna cum laude from Yale University with a B.S. in Molecular, Cell, and Development in Biology and distinction in her major. Anjali Walia is a fourth-year medical student. She was also elected to the prestigious Phi Beta Kappa honor society. She achieved a perfect score (528/528) on the MCAT. At Yale, she published pulmonary research and led numerous reproductive justice advocacy efforts. She was finalist (Top 20) of the U.S. Chemistry Olympiad and obtained a perfect score on the SAT (1600/1600).

Scores:

  • MCAT: 528/528
  • SAT: 1600/1600
  • AP Biology: 5
  • AP Chemistry: 5
  • AP Physics I: 5
  • AP Physics C: 5
  • AP Computer Science: 5
  • AP Calculus: 5
  • AP English Language and Composition: 5
  • AP English Literature and Composition: 5

Casey

Perfect Score

Casey Vickstrom graduated summa cum laude from Northwestern University in 2014 with a B.A. in Biological Sciences. He is a third-year medical student in the MD/PhD program at the Medical College of Wisconsin, having completed his PhD in Neuroscience in 2020. His research focused on neural circuits and endocannabinoids related to anxiety and depression. He aims to study mechanisms of neurological diseases to identify new therapeutic targets. Casey has extensive tutoring experience for Step 1 and plans to pursue a career in neurology or related specialties. In his free time, he enjoys skiing, soccer, and spending time with family, friends, and his dog.

  • Education:
  • Northwestern University B.A.Honors
  • Medical College of Wisconsin
  • Medical Scientist Training Program (MD/PhD) at present
  • Score:
  • Step 1 - 265/300
  • ACT - 35/36
  • AP Biology - 5/6
  • MCAT - 515/528
  • Biology / Organic chem - 131/136
  • Physical Sciences - 127/136
  • Reading - 127/136

Mike

Perfect Score

  • Education:
  • Georgetown University, B.S.
  • Medical school/Residency:
  • Rutgers Robert Wood Johnson Medical School, M.D.
    Orthopedics Surgery
  • MCAT: 528 / 528
  • USMLE Score:
  • Step 1 - Pass
  • Step 2CK - 245
  • Step 3 - 252
  • SAT Subject Test –
  • Biology (Molecular): 780 / 800
  • Mathematics Level 2: 780 / 800
  • Mathematics Level 1: 750 / 800
  • SAT with Essay: 2330 / 2400
  • Reading: 800 / 800
  • Writing: 770 / 800
  • Math: 760 / 800
  • Chem/Phys: 131 / 136
  • CARS: 131 / 136
  • Bio/Biochem: 130 / 136
  • Psych/Soc: 130 / 136
  • AP Biology: 5 / 5
  • AP Statistics: 5 / 5
  • AP Calculus: 5 / 5
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