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NAPLEX online course review

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Mastering pharmacokinetics and drug interactions key for NAPLEX  

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Comprehensive Pharmacology Principles Learn to use pharmacological knowledge in patient care effectively. Get a concise review packed with focused facts.

Essential Drug Information Course content simplifies vital drug interaction, therapeutic outcome, and patient counseling info.

Detailed Pharmaceutical Insights Visual aids clarify pharmaceutical concepts with detailed images and illustrations.

Complete NAPLEX online prep course review

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Advanced Pharmacotherapy Concepts Deepen your understanding of complex pharmacotherapy regimens and their practical applications in patient care. Concise review with focused insights.

Critical Medication Knowledge Streamline your study with a layout that distills critical drug information, patient safety practices, and counseling points.

Visual Learning in Pharmacy Explore pharmaceutical sciences through detailed visual aids such as charts, tables, diagrams, and step-by-step process illustrations.

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Extensive Qbank Across Core Areas:

Our NAPLEX® Qbank, with over 498+ meticulously crafted questions, covers diverse subjects and topics, ensuring you have a broad and in-depth practice experience.

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Designed by top-performing pharmacists, our NAPLEX® Qbank offers premium questions for deep comprehension, sharpening your proficiency for the actual exam.

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The course is a comprehensive review of every subject and trains you how to successfully approach difficult, complex concepts. Study for any topic anytime, anywhere.

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Name 3 classes of drugs that St John’s Wort can interact with:

Explanation

  • HIV antiretrovirals (CYP3A4 substrates)
  • SSRIs (may increase risk of serotonin syndrome) 
  • Clarithromycin (CYP3A4 substrates)

*not an all-inclusive list*

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Name three examples of drugs that can worsen tachycardia, a major symptom of anxiety.

Explanation

Levothyroxine (can lead to hyperthyroidism, a common symptom of which is a rapid heartbeat)

Amphetamines (ADHD medication and CNS stimulant)

Caffeine (CNS stimulant)

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ADHD is a chronic neurodevelopmental disorder. Much research has been done on this topic. What kinds of pathways might be affected in a patient with ADHD?

Explanation

Dopaminergic pathways may be damaged due to exposure to hazards or brain injury.

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List 1 black box warning of methylphenidate. List 1 contraindication. List 1 major drug interaction.

Explanation

BBW: high risk of abuse

Contraindication: current or recent MAOI use within 14 days

Interaction: avoid with alcohol

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Explain the difference between a time dependent killer and a concentration dependent killer

Explanation

A time dependent killer, such as a penicillin, relies on frequent dosing intervals to maximize the time spent above the MIC.

A concentration dependent killer, such as an aminoglycoside, relies on high doses at lower intervals to raise the concentration of the drug to a level that is significantly higher than that of the MIC.

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You are a pharmacist working at a community pharmacy. The pediatrician’s office down the street sends you a prescription for doxycycline for a 7-year-old male patient.

The patient’s mother comes to your pharmacy to ask you if doxycycline is safe for her son to take. What do you tell her?

Explanation

Doxycycline should not be used in children under the age of 8, as this drug tends to permanently discolor the teeth in young children.

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A patient presents to the primary care provider with a sore throat, pain on swallowing, and white spots in the back of the throat. The physician performs a culture and confirms that it is strep throat. He sends a prescription to your pharmacy for penicillin VK 250 mg PO QID. When the patient comes to pick up the medication, you see a documented anaphylaxis reaction to penicillins. You call the doctor to inform him of this, and he asks for alternative recommendations. What are some recommendations you can give to the doctor?

Explanation

Clarithromycin, azithromycin, or clindamycin can be considered. Treatment duration for clarithromycin and clindamycin should be for 10 days. Treatment with azithromycin should be for 5 days.

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True or false: primaquine is the drug of choice for dengue fever.

Explanation

False. Primaquine is an anti-protozoal drug used for the prophylaxis and management for malaria, another mosquito borne illness.

In fact, there is no current medication for dengue. Instead, it is managed by symptomatic relief and vaccination.

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The dose needed to treat severe pain with opioid drugs is determined by the severity of the pain as well as the patient’s ____________ (assuming they are not opioid-naive)?

Explanation

Tolerance.

What eventually leads to addiction to opioid drugs is that tolerance will develop to all of them over time. Increasing doses will be needed to maintain the same level of pain control.

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In a patient that is being switched from Morphine 100mg daily to hydromorphone, the dose of hydromorphone initially prescribed would be 12.5mg daily?

Explanation

True.

The answer to this question is not necessarily hard, but certainly does require some thought. Hydromorphone has an MME of 4:1. Therefore, to get morphine 100mg per day, only 25mg of hydromorphone is needed. However, when switching among opioid drugs it is best to reduce the starting dose of the new drug by 50% to avoid overdosing from incomplete cross-tolerance across opioid sub-receptors. Therefore, 25mg/2 = 12.5mg daily.

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High-Yield Flashcards by Subjects and Topics:

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Management of Care 17% - 23%

 

Management of Care represents the majority of content found on the exam, accounting for 17-23% of test questions covering nursing care and protecting the patient as well as health care personnel. The course includes a comprehensive, yet concise review of high yield topics to help you successfully apply concepts and processes to prepare you for the largest content category of the exam.

  • Advance Directives
  • Advocacy
  • Assignment
  • Delegation and Supervision
  • Case Management
  • Client Rights
  • Establishing Priorities
  • Ethical Practice
  • Informed Consent
  • Information Technology
  • Performance Improvement
  • Referrals
  • Collaboration with Interdisciplinary Team
  • Concepts Of Management
  • Confidentiality and Information Security
  • Continuity Of Care
  • Legal Rights and Responsibilities

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Safety and Infection Control 12%

 

Safety and Infection Control makes up roughly 12% of the exam. The course covers the full range of high yield topics included in this category with a focus on protecting patients and healthcare personnel from environmental and health hazards. Topics covered help you understand how to apply concepts for the exam with high quality images, charts, and diagrams included.

  • Accident
  • Error and Injury Prevention
  • Emergency Response
  • Ergonomic Principles
  • Handling Hazardous
  • Infectious Materials
  • Home Safety
  • Incident Reporting and Irregular
  • Occurrence/Variance
  • Safe Use of Equipment
  • Security Plan
  • Standard Precautions
  • Transmission-Based Precautions
  • Surgical Asepsis
  • Use Of Safety Devices and Restraints

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Health Promotion and Maintenance Content Review 9%

 

Health Promotion and Maintenance represents approximately 9% of the exam and incorporates knowledge of growth and development, prevention and early detection of health problems, and strategies to achieve optimal health. The course helps you learn, understand, and apply concepts covering every topic from this section of the test. Each topic is clearly defined and explained throughout with high quality images, graphs and diagrams to help you score above the passing standard.

  • The Aging Process
  • Ante/Intra/Postpartum and Newborn Care
  • Developmental Stages and Transitions
  • Health Promotions and Disease Prevention
  • Health Screening
  • High Risk Behaviors
  • Lifestyle Choices
  • Self-Care
  • Techniques Of Physical Assessment

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Psychosocial Integrity Content Review9%

 

Approximately 9% of the exam will cover nursing topics and principles related to psychosocial integrity. The course contains a detailed and comprehensive high yield overview of nursing care practices that promote and support emotional, mental, and social well-being of patients experiencing stressful situations, as well as those with acute or chronic mental illnesses. Gain a deeper understanding of important information and learn how to apply concepts for every topic covered on the examination.

  • Abuse/Neglect
  • Behavioral Interventions
  • Dependencies and Substance Use Disorders
  • Coping Mechanisms
  • Crisis Intervention
  • Cultural Awareness and Influences on Health
  • End-Of-Life Care
  • Family Dynamics
  • Grief And Loss
  • Mental Health Concepts
  • Religious And Spiritual Influences on Health
  • Sensory And Perceptual Alterations
  • Stress Management
  • Support Systems
  • Therapeutic Communication and Environment

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Basic Care and Comfort Content Review 9%

 

Basic care and comfort is a less intensive content section of the exam (9%), but still a highly important category focused on providing comfort and nursing assistance in the performance of activities of daily life. The course contains detailed, yet concise high yield content that covers each topic found on the exam to help you understand how to apply concepts.

  • Assistive Devices
  • Elimination
  • Mobility and Immobility
  • Non-pharmacological Comfort Interventions
  • Nutrition and Oral Hydration
  • Rest and Sleep
  • Personal Hygiene

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Pharmacological and Parenteral Therapies Content Review

 

Pharmacology and parenteral therapies are another big and important section of the exam, representing 12-18% of test items focused on the administration of medications. The course highlights core concepts and key principles from each topic that help you understand how to apply concepts, and includes high quality images, diagrams, and tables to successfully prepare for this category.

  • Adverse Effects
  • Side Effects
  • Interactions
  • Contraindications
  • Blood and Blood Products
  • Central Venous Access Devices
  • Clinical Math and Dosage Calculations
  • Expected Actions and Outcomes
  • Medication Administration
  • Parenteral and Intravenous Therapies
  • Pharmacological Pain Management
  • Total Parenteral Nutrition

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Reduction of Risk PotentialContent Review 12%

 

Reduction of risk potential makes up about 12% of the exam content. The course provides high-yield concepts on reducing the likelihood of developing complications related to existing conditions, treatments, or procedures, giving you an in-depth understanding of the application of difficult concepts in clinical scenarios on the exam. Each topic is covered in detail with clear concepts and high-quality visuals, providing you with essential information to quickly master this exam category.

  • Changes and Abnormalities in Vital Signs
  • Diagnostic Testing
  • Lab Values
  • Potential for Alterations in Body Systems
  • Potential for Complications of Diagnostic Tests
  • Treatments And Procedures
  • Potential for Complications from Surgical Procedures and Health Alterations
  • System-Specific Assessments
  • Therapeutic Procedures

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Physiological Adaptation Content Review14%

 

The category of physiological adaptation represents approximately 14% of exam content. The course covers this section with a high yield focus on managing and providing care for patients with chronic, acute or life threatening physical health conditions. The course chapters include core concepts and in-depth explanations for each topic to help you understand how to apply key information, concepts, and processes to effectively prepare for every test item.

  • Fluid and Electrolyte Imbalances
  • Hemodynamics
  • Illness Management and Medical Emergencies
  • Pathophysiology
  • Unexpected Response to Therapies
  • Alterations in Body Systems

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Respiratory System Content Review9% - 13%

 

The UMock USMLE® Step 1 prep course provides a condensed, high-yield review of concepts to help you fully understand normal and abnormal pulmonary processes, and how to apply knowledge to clinical scenarios relating to pathologies that affect the lungs, pulmonary function tests, ventilation/perfusion mismatch, and cell types and their function based on their location in the respiratory tract.

The course includes volume calculations as well as high quality graphs and diagrams to help you learn exactly what is tested from each topic, and how to apply it to respiratory medicine.

  • Cancers of the Lungs
  • Pulmonary Vascular Disease
  • Restrictive Pulmonary Disease
  • Miscellaneous Disorders of the Lungs
  • Tumors of the Upper Respiratory Tract
  • Chronic Obstructive Pulmonary Disease
  • Disorders of the Upper Respiratory Tract

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Gastrointestinal Tract Content Review5% - 9%

 

The gastrointestinal system represents roughly 5-9% of test items. The UMock USMLE® Step 1 prep course gives you a comprehensive and concise review of high-yield material to help you memorize, understand, and apply information to clinical scenarios pertaining to concepts of digestion and how one factor is affected by another, malabsorption syndromes, as well as the histopathology type of each location, and where the pharmacotherapies take action.

The course features high quality diagnostic images and microscopic views covering normal and abnormal processes of diseases to help you accurately interpret and apply concepts in gastroenterology for the exam.

  • Diseases of the Colon
  • Diseases of the Appendix
  • Diseases of the Stomach
  • Diseases of the Esophagus
  • Diseases of the Mouth and Jaw
  • Diseases of the Small Intestine
  • Diseases of the Salivary Glandsw

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Renal and Urinary System Content Review9% - 13%

 

The renal and urinary system make up questions heavily weighted on physiology-focused concepts. The UMock USMLE® Step 1 prep course provides a high-yield review of essential concepts in a clear and concise format to help you understand and apply the connection between renal tubule physiology and the diuretics that work on the tubule, as well as applying concepts in nephritic and nephrotic syndromes to clinical scenarios.

The course includes high quality radiological images and microscopic views highlighting normal and abnormal processes specific to renal and urinary diseases to give you a distinguished understanding of the application of concepts in clinical scenarios.

  • Hemodynamic
  • Urolithiasis
  • Hemodynamic
  • Renal Failure
  • Nephrocalcinosis
  • Glomerular Diseases
  • Cystic Diseases of Kidney
  • Hemodynamic Dysfunction
  • Urinary Tract Obstruction
  • Diffuse Cortical Necrosis
  • Nonrenal Causes of Azotemia
  • Infection of the Urinary Tract and Kidney
  • Congenital Anomalies of the Urinary Tract
  • Tumors of the Kidney, Urinary Tract, & Bladder
  • Tubular and Interstitial Disorders of the Kidney

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Male Reproductive System Content Review9% - 13%

 

In the reproductive system, the UMock USMLE® Step 1 prep course covers the male and female reproductive system as well as pregnancy, childbirth, and the puerperium. The course provides high-yield topics concentrated on clear and concise explanations to help you understand and apply concepts to clinical scenarios associated with the hormonal pathways of the male and female reproductive systems.

The course integrates concepts with high quality microscopic views and diagnostic images to help you improve recall of normal and abnormal processes in disease and apply it to clinical scenarios like you’ll see on the exam.

  • Diseases of the Penis
  • Diseases of the Testes
  • Diseases of the Prostate

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Female Reproductive System Content Review9% - 13%

 

In the reproductive system, the UMock USMLE® Step 1 prep course covers the male and female reproductive system as well as pregnancy, childbirth, and the puerperium. The course provides high-yield topics concentrated on clear and concise explanations to help you understand and apply concepts to clinical scenarios associated with the hormonal pathways of the male and female reproductive systems.

The course integrates concepts with high quality microscopic views and diagnostic images to help you improve recall of normal and abnormal processes in disease and apply it to clinical scenarios like you’ll see on the exam.

  • Ovaries
  • Breast
  • Vulva & Vagina
  • Uterine Cervix
  • Uterine Corpus
  • Fallopian Tubes
  • Disorders of Pregnancy

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Endocrine System Content Review9% - 13%

 

The UMock USMLE® Step 1 prep course combines concise high yield topics with detailed diagrams covering normal and abnormal processes of endocrine-specific pathologies and physiologies. The course helps you gain a clear understanding of how to apply concepts to clinical scenarios for keeping hormone levels in balance, diagnostic testing, treatment, and management.

The course includes descriptive illustrations, microscopic views, images, and graphs highlighting heavily test exam content to help you gain a full understanding of applying concepts for normal and abnormal processes of the endocrine system.

  • Endocrine Pancreas
  • Endocrine of Pituitary
  • Endocrine of Thyroid Gland
  • Endocrine of Adrenal Glands
  • Endocrine of Parathyroid Glands
  • Multiple Endocrine neoplasia (MEN) Syndrome

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Dermatology Content Review6% - 10%

 

In Dermatology, the UMock USMLE® Step 1 prep course gives you concise, high yield topics to help you understand how to apply basic concepts to clinical scenarios in comparing similar pathologies based on the morphology and distribution of conditions.

Every topic is covered for both normal and abnormal body-system processes with high quality microscopic views and gross images to help you visually understand the application of medicine specific to diseases in skin and subcutaneous tissue.

  • Pruritus
  • Urticaria
  • Common Rashes
  • Infestations
  • Bites & Stings
  • Hair Disorders
  • Common Neoplasms
  • Acneiform Eruptions
  • Common Skin Infections
  • Cuts, Scrapes, & Burns
  • Foot and Leg Ulcers
  • Nail Disorders
  • Disorders of Mucous Membranes
  • Autoimmune Blistering Diseases
  • Therapeutic Principles in Dermatology
  • Dermatologic Urgencies and Emergencies
  • Cutaneous Manifestations of Internal Disease
  • Dermatologic Problems of Special Populations

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Nervous System Content Review4% to 7%

 

Exam items covering the nervous system represent about 4-7% of test questions. The UMock Step 1 Prep Course clearly explains gross anatomy and neuroanatomy and normal and abnormal processes from this area, including

  • Embryonic development
  • Fetal maturation
  • Perinatal changes
  • Neural tube derivatives
  • Cerebral ventricles
  • Neural crest derivatives
  • Organ structure & function
  • Cell & tissue structure & function
  • Repair
  • Regeneration
  • Changes associated with life stages
  • Infectious
  • Immunologic
  • Inflammatory disorders
  • Neoplasms
  • Cerebrovascular disease
  • Disorders related to spinal cord
  • Spine
  • Spinal nerve roots
  • Cranial & peripheral nerve disorders
  • Neurologic pain syndromes
  • Degenerative disorders
  • Global cerebral dysfunction
  • Neuromuscular
  • Metabolic disorders
  • Paroxysmal disorders
  • Sleep disorders
  • Traumatic & mechanical disorders
  • Increased intracranial pressure
  • Congenital disorders
  • Disorders of the eye & eyelid
  • Disorders of the ear
  • Movement disorders

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Rheumatology and Musculoskeletal Content Review6% - 10%

 

The UMock USMLE® Step 1 prep course provides the most valuable exam information with a complete and concise review of high-yield topics to help you quickly understand and apply knowledge to clinical scenarios covering the diagnosis of joint pathologies, and anatomical paths of distal branches and the muscles that they innervate.

The course features detailed tables and high quality radiologic and gross images to help you conceptualize the application of medicine for normal and abnormal body system processes and pathologies in rheumatology and the musculoskeletal system.

  • Diseases of Skeletal Muscle
  • Diseases of Bone
  • Diseases of Joints
  • Soft-Tissue Tumors

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Behavioral Science Content Review8% to 13%

 

Behavioral science accounts for roughly 8-13% of exam questions. The UMock USMLE® Step 1 prep course helps you clarify difficult concepts in the mind-body relationship, and understand how to apply DSM-IV and DSM-5 diagnostic criteria in the manifestations of psychological disorders to various clinical scenarios with a high-yield, concise review of concepts covering every topic for normal and abnormal processes.

The course includes descriptive diagrams, tables, and images to provide a concentrated review of material to help you fully understand the application of behavioral science to clinical medicine.

  • Sexuality
  • Learning Theory
  • Beginning of Life
  • Anxiety Disorders
  • Aggression & Abuse
  • Psychosomatic Medicine
  • Somatic Symptom Disorders
  • Obsessive-Compulsive Disorders
  • Trauma & Stressor-Related Disorders
  • Substance-related Disorders
  • Sleep & Sleep-wake Disorders
  • Psychological Therapies
  • Family, Culture, & Illness
  • Psychiatrics Disorders in Children
  • Aging, Death, & Bereavement
  • School Age, Adolescence, & Adulthood
  • Psychoanalytic Theory & Defense Mechanisms
  • Depressive Disorders & Bipolar Disorders
  • Schizophrenia Spectrum & other Psychotic Disorders
  • Clinical Assessment of Patients with Behavioral Symptoms
  • Biological Assessment of Patients with Psychiatric Symptoms
  • Neurocognitive, Personality, Dissociative & Eating Disorders

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Embryology Content Review11% - 15%

 

In Embryology, the UMock USMLE® Step 1 prep course presents high-yield content in a concise format that helps you understand and quickly recall concepts in human development and congenital malformations, and apply the connection between embryological knowledge and clinical medicine. The course further clarifies key facts and concepts to help you maximize comprehension and visual understanding in applying concepts with high quality diagnostic, radiographic, and clinical images.

  • Skeletal System
  • Muscular System
  • Upper Limb
  • Lower Limb
  • Body Cavities
  • Pregnancy
  • Teratology
  • Head & Neck
  • Prefertilization Events
  • Human Development - Week 1
  • Human Development - Week 2
  • Embryonic Period
  • Cardiovascular System
  • Placenta & Amniotic Fluid
  • Embryology of the Ear
  • Embryology of the Eye
  • Embryology of the Nervous
  • Embryology of the Digestive
  • Embryology of the Respiratory
  • Urinary System
  • Female Reproductive System
  • Male Reproductive System
  • Integumentary System

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Women’s Health and Pregnancy Content Review3% to 5%

 

The musculoskeletal system accounts for roughly 3-5% of the exam. Learn everything covered on this section of the exam for normal and abnormal process with the UMock Step 1 Prep Course:

  • Tendon
  • Repair
  • Joints
  • Usage
  • Muscles
  • Cartilage
  • Arthritis
  • Infectious
  • Regeneration
  • Blood supply
  • Gross anatomy
  • Neoplasms
  • Embryonic development
  • Organ structure & function
  • Changes associated with life stages
  • Cell & tissue structure & function
  • Ligaments & fascia
  • Traumatic & mechanical disorders
  • Mechanism of the action of drugs
  • Fetal maturation & perinatal changes
  • Inflammatory & immunologic disorders
  • Adverse effects on the musculoskeletal system
  • Degenerative & metabolic disorders of bone

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Histology Content Review8% to 13%

 

Histology makes up about 8-13% of questions on the exam. The UMock USMLE® Step 1 prep course offers a high-yield review condensed concepts format to help you better understand the relationship between cell structure and function to biological tissues, and effectively apply concepts to clinical scenarios on the exam. The course includes high quality micrographs, illustrations, and tables to further enhance your ability to quickly recall concepts and how they apply in clinical practice.

  • Cell Histology
  • Extracellular Matrix
  • Epithelia & Glands
  • Connective Tissue
  • Blood & Hemopoiesis
  • Histology Cartilage & Bone
  • Histology Muscle
  • Nervous Tissue
  • Circulatory System
  • Histology of Lymphoid
  • Histology of Endocrine
  • Histology of Skin
  • Histology of Respiratory
  • Histology of Digestive
  • Urinary Glands
  • Female Reproductive
  • Male Reproductive
  • Special Senses
  • Cavity and Alimentary Tract

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Anatomy Content Review11% to 15%

 

In Anatomy, the UMock USMLE® Step 1 prep course presents the most important high-yield facts you need to memorize for the exam, and helps you understand and apply clinical correlations of the structure and organization of the body to clinical scenarios such as fractures, trauma, and injuries. The course is illustrated with high quality descriptive images of anatomic relationships to further enhance your ability to apply knowledge to concepts.

  • Perineum
  • Vertebral Column
  • Spinal Cord & Spinal Nerves
  • Autonomic Nervous System
  • Lymphatic System
  • Chest Wall
  • Anatomy of the Heart
  • Abdominal Wall
  • Kidney, Ureter, Bladder, & Urethra
  • Suprarenal Glands
  • Abdominal Vasculature
  • Abdominal Viscera
  • Anatomy of the Pelvis
  • Spleen
  • Female Reproductive
  • Male Reproductive
  • Anatomy of the Upper Limb
  • Anatomy of the Lower Limb
  • Anatomy of the Head
  • Anatomy of the Neck
  • Anatomy of the Eye
  • Anatomy of the Ear
  • Pleura, Tracheobronchial Tree, & Lungs
  • Sigmoid Colon, Rectum, & Anal Canal

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Neuroanatomy Content Review9% to 13%

 

In Neuroanatomy, the UMock USMLE® Step 1 prep course provides high-yield concepts in a clear and concise presentation to help you thoroughly understand and apply concepts in clinical scenarios covering different pathways and tracts, patterns, distribution territories, and the results of lesions.

In Neurology, the UMock USMLE® Step 1 prep course offers a clear and concise approach to helping you understand and apply concepts to clinical scenarios with high yield concepts covering the relationship between nerves and neurotransmission, and neurologic disease

The course features high quality illustrations, detailed tables, and radiologic images for both normal and abnormal processes to help you better understand how to apply concepts for diagnosis, treatment and management of neurologic diseases.

  • Cerebellum
  • Neurohistology
  • Cranial nerves
  • Auditory System
  • Vestibular System
  • Cerebral Cortex
  • Visual System
  • Gross Anatomy of the Brain
  • Tracts of the Trigeminal system
  • Meninges & Cerebrospinal Fluid
  • Development of the Nervous System
  • Olfactory, Gustatory, & Limbic
  • Autonomous Nervous System
  • Neurotransmitters & Pathways
  • Diencephalon: Thalamus & Hypothalamus
  • Blood supply of the Central Nervous System
  • Tracts & Lesions of the Spinal Cord & Brainstem
  • Tracts & Lesions of the Spinal Cord & Brainstem
  • Basal Nuclei & the Extrapyramidal Motor System

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Legal and Ethics Content Review6% to 10%

 

The UMock USMLE® Step 1 prep course gives you a clearly explained review of high-yield topics to help you understand how to apply, and make a decision in clinical scenarios involving calculated risks, promoting the patients’ best interest, and respecting the patient’s decisions about their own health. Topics from the course include:

  • Minors
  • Abortion
  • Refusing Care
  • Confidentiality
  • Informed Consent
  • Abuse & Neglect
  • Reportable Diseases
  • Ethical Principles
  • Healthcare Legislation
  • Capacity & Competency
  • Physician Assisted Suicide

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Biostatistics and Epidemiology Content Review4% to 6%

 

Biostatistics and Epidemiology covers roughly 4-6% of exam questions. The UMock USMLE® Step 1 prep course clarifies difficult concepts with a concise review of high-yield concepts. The course eliminates excessive detail to help you memorize and understand how to efficiently identify and extract the most important information, and apply your knowledge to concepts and formulas. The course includes high quality graphs and tables that clearly illustrate the most important and heavily tested concepts you need to know how to apply for the exam, including:

  • Research Methods
  • Hypothesis Testing
  • Descriptive Statistics
  • Differential Statistics
  • Assessing the Evidence
  • Correlational & Predictive Techniques
  • Statistics in Medical Decision Making
  • Epidemiology & Population Health

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Biostatistics and Epidemiology Content Review4% to 6%

 

Biostatistics and Epidemiology covers roughly 4-6% of exam questions. The UMock USMLE® Step 1 prep course clarifies difficult concepts with a concise review of high-yield concepts. The course eliminates excessive detail to help you memorize and understand how to efficiently identify and extract the most important information, and apply your knowledge to concepts and formulas. The course includes high quality graphs and tables that clearly illustrate the most important and heavily tested concepts you need to know how to apply for the exam, including:

  • Research Methods
  • Hypothesis Testing
  • Descriptive Statistics
  • Differential Statistics
  • Assessing the Evidence
  • Correlational & Predictive Techniques
  • Statistics in Medical Decision Making
  • Epidemiology & Population Health

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Ligand-Receptor Interactions

 
  • Receptors
    • Membrane Permeability
    • Electrical Signaling
    • The Action Potential
    • Voltage-Gated Ion Channels
    • Ligand-Gated Ion Channels
    • Signal Transduction
    • G-Protein Coupled Receptors
    • Enzymatic Activity
    • Regulation of GPCRs
    • Examples of GPCRs
    • Nuclear Hormone Receptors
    • Nuclear Hormone Receptor Structure
    • Activation of Nuclear Hormone Receptors
    • Glucocorticoid Receptor
    • Selective Receptor Modulators
    • Constitutively Active Receptors
  • Intro To Interactions
  • Ligand-Receptor Interactions
    • Overview
    • Enzyme Interactions
    • Receptor Affinity
  • Kinase Activity
    • Serine and Threonine Kinases
    • Tyrosine Kinases
    • Tyrosine Kinase-Linked Receptors
    • Insulin Receptors
    • Downstream Cellular Signaling

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Intro to Pharmacodynamics

 
  • The Mechanisms of DrugAction
    • Overview
  • Chemical Interactions
    • Additive
    • Synergistic
    • Potentiation
    • Antagonism
    • Drug-Receptor Binding
    • Spare Receptors
    • Fractional Effect
    • Controls of Fractional Effect
  • Dose-Response
    • Overview
    • Dose-Response Curves
    • Quantal Dose-Response
    • Sigmoid Dose-Response Curve
    • Regulation of Drug Responses
  • Agonists and Antagonists
    • Overview
    • Antagonists
    • Agonists

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Intro to pharmacokinetics Content Review

 
  • Absorption
    • Overview
    • Factors Impacting Drug Absorption
    • The Digestive System
    • Bioavailability
  • Distribution
    • Factors Impacting Distribution
    • Protein Binding
    • Volume of Distribution
    • Inhibition to Drug Distribution
  • Excretion
    • The Kidney
    • Clearance
    • Rate of Elimination
  • Additional Pharmacokinetic Parameters
    • Compartment Models
    • Elimination Rate Constant
    • Order of Kinetics
    • Michaelis-Menten Kinetics
    • Predicting Drug Concentrations
    • Half-Life
    • Steady-State
    • Loading Dose
    • Monitoring Therapy
  • Metabolism
    • Overview
    • First-Pass Metabolism
    • The Liver
    • Phase I Reactions
    • Types of Phase I Reactions
    • Phase II Reactions
    • Types of Phase II Reactions
    • Metabolism Overview

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Drug interactions Content Review

 
  • Overview
  • Pharmaceutical Drug Interactions
  • Pharmacodynamic Drug Interactions
  • Other Types of Drug Interactions
  • Pharmacokinetic Drug Interactions
    • Absorption
    • Distribution
    • Metabolism
    • Elimination

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Pharmacogenomics Content Review

 
  • Precision Medicine
    • Biomarkers
    • Polymorphisms
    • Polymorphism Nomenclature
    • Linkage Disequilibrium
    • Tag-SNPs
    • Phase II Polymorphisms
    • Other Testing
    • Dosing Recommendation Resources

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AllergiesContent Review

 
  • Hypersensitivity Reactions
    • Specimen collection
    • Type I Hypersensitivity Reactions
    • Type II Hypersensitivity Reactions
    • Type III Hypersensitivity Reactions
    • Type IV Hypersensitivity Reactions
  • Allergic Rhinitis
    • Overview
    • Categorization
    • Risk Factors
    • Preventative and Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
    • Intranasal Drug Delivery
  • Cough and Cold
    • Overview
    • Herbal Remedies/Supplements
    • Pharmaceutical Treatments
    • Pediatric Cough and Cold Treatments
    • Cough and Cold Combination Formulations

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Drug Allergies Content Review

 
  • Drug Allergies
    • Immune Response
    • Mitigating Reactions
    • Adverse Reactions
  • Common Drug Allergies
    • Sulfa Drugs
    • Biologics
    • Beta-Lactams
    • Opioids
    • Heparin
    • NSAIDS
    • Food Allergies
    • Penicillin

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Transplants Content Review

 
  • Immunosuppression
    • Blood Types
    • Induction Drug Therapy
    • Maintenance Drug Therapy
  • Graft Rejection
    • Cellular Mediated Rejection
    • Antibody Mediated Rejection
  • Organ Transplant Complications
    • Metabolic Syndrome
    • Cancer
    • Infection

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Autoimmune Content Review

 
  • Autoimmune Disorders
    • Symptoms
    • Detection
    • Treatment
  • Rheumatoid Arthritis
    • Clinical Features
    • Diagnosis
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
    • Patient Counseling
  • Psoriasis
    • Overview
    • Presentation
    • Treatments
    • Pharmaceutical Treatments
  • Celiac Disease
    • Cause
    • Clinical Features
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
  • Multiple Sclerosis
    • Clinical Features
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
    • Symptom Control Treatments
    • Patient Counseling
  • Sjogren’s Syndrome
    • Overview
    • Clinical Presentation
    • Dry Mouth Treatments
    • Dry Eye Treatments
  • Myasthenia Gravis
    • Symptoms
    • Treatment
    • Drugs that Exacerbate Myasthenia Gravis
  • Systemic Lupus Erythematosus
    • Disease Course
    • Activating Factors
    • Drug Induced Lupus Erythematosus
    • Clinical Features
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
  • Raynaud’s Phenomenon
    • Overview
    • Presentation and Symptoms
    • Pharmaceutical Treatment
    • Drug-Induced Raynaud’s

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The Respiratory System Content Review

 
  • Overview
    • Gas Exchange
    • Other Organs Involved
  • Anatomy and Function
    • Upper Respiratory Tract
    • Lower Respiratory Tract
  • Drug Delivery
    • Systemic Delivery
    • Localized Delivery
  • Lung Capacities
    • Spirometry
  • Homeostatic Acid-Base Balance
    • Identifying Lab Values
    • Acidosis
    • Alkalosis
    • Clinical Features
    • Respiratory Compensation
    • Renal Compensation
    • Anion Gap

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Pulmonary Vascular Resistance Content Review

 
  • Overview
    • Poiseuille’s Law
    • Mechanisms
    • Pathophysiology
    • Clinical Presentation
  • Regulation of Pulmonary Vascular Resistance

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Pulmonary Hypertension Content Review

 
  • Overview
    • Classifications
  • Clinical Features of Pulmonary Arterial Hypertension
    • Symptom Classifications
    • Treatment / Cure
  • Pathophysiology
    • Imbalance of Endogenous Vaso-modulators
    • Imbalance of Cell Regulation
    • Diagnosis
  • Non-Pharmaceutical Treatments
  • Pharmaceutical Treatments
    • Immunizations
    • Supportive Therapies
    • Soluble Guanylate Cyclase Stimulator
    • Phosphodiesterase-5 Inhibitors
    • Receptor Agonists and Proteinoids
    • Endothelin Receptor Antagonists
  • Pulmonary Fibrosis
    • Overview
    • Clinical Features
  • Drug Interactions
    • Soluble Guanylate Cyclase Stimulator: Riociguat
    • Phosphodiesterase-5 Inhibitors
    • Prostacyclin Receptor Agonists and Prostacyclin Analogs
    • Endothelin Receptor Antagonists

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Obstructive DiseasesContent Review

 
  • COPD
    • Overview
    • Classification
    • Causes
    • Diagnosis
    • Clinical Features
    • Asthma Classifications
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
    • Theophylline, Leukotriene Receptor Antagonists, mAbs
    • Additional Treatments
    • Special Patient Populations and Circumstances
  • Emphysema
    • Overview

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Cystic Fibrosis Content Review

 
  • Overview
    • Pathophysiology
    • Incidence
    • Inheritance
    • CFTR Mutation
    • Clinical Features
    • Non-Pharmaceutical Treatments
    • Pharmaceutical Treatments
    • Patient Counseling

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Acute and Critical Care Content Review

 
  • Overview
    • Acute Care
    • Intensive Care Unit
  • Venous Thromboembolism
    • Causes
    • Deep Vein Thrombosis
    • Clinical Presentation
    • Comorbidities
    • Prevention
  • Ventilators
    • Ventilator-Induced Lung Injury
    • Ventilator-Induced Infections
  • Common Conditions in the Intensive Care Unit
    • Pain
    • Delirium
    • Agitation
  • More Drugs used in the ICU and the Operating Room
    • Anesthetics
    • Neuromuscular Blocking Drugs
    • Hemostatic Drugs
  • Pulmonary Embolism
    • Adverse Side Effects

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The Heart Content Review

 
  • Anatomy and Function
  • Flow of Blood

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Dyslipidemia Content Review

 
  • Non-Pharmaceutical Treatments
  • Pharmaceutical Treatments
    • Concerns
    • Lomitapide
    • Mipomersen
    • Ezetimibe
    • Statins
    • Fish Oils
    • Peroxisome Proliferator Receptor Alpha Activators
    • Bile Acid Sequestrants
    • Proprotein Convertase Subtilisin Kexin Type 9 Inhibitors
    • Niacin
  • Overview
    • Classifications
  • Diagnostic Criteria
    • Clinical Features

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Hypertension Content Review

 
  • Overview
  • Clinical Features
    • Pathophysiology
    • Compensation
  • Diagnostic Criteria
  • Treatment
    • Non-Pharmaceutical Treatments
    • Special Populations
    • Pharmaceutical Treatments
  • Vasodilators
    • Drug Interactions
    • Patient Counseling
  • Calcium Channel Blockers
    • Drug Interactions
    • Patient Counseling
  • Renin-Angiotensin Aldosterone System Inhibitors
    • Drug Interactions
    • Patient Counseling
  • Diuretics
    • Thiazide-Type
    • Potassium-Sparing
  • Beta-Blockers
    • Drug Interactions
    • Patient Counseling
  • Alpha-Receptor Modulators
    • Alpha-2 Adrenergic Agonists
    • Alpha Blockers
  • Acute and Critical Hypertensive Care

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Ischemic Heart Disease Content Review

 
  • Overview
  • Clinical Features
    • Pathophysiology
  • Diagnostic Criteria
  • Non-Pharmaceutical Treatments
  • Pharmaceutical Treatments
    • Antiplatelet Agents
    • Nitroglycerin
    • Antianginal Therapy

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Arrythmias Content Review

 
  • Overview
    • Clinical Features
    • Pathophysiology
  • Arrythmia Diagnostic Criteria
    • Normal Sinus Rhythm
    • Abnormal Sinus Rhythm (Arrythmia)
  • Arrythmias
    • Antiarrhythmics
    • Class I Antiarrhythmics
    • Class III Antiarrhythmics
    • Class IV Antiarrhythmics

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Myocardial Infarction Content Review

 
  • Overview
  • Clinical Features
  • Diagnostic Criteria
  • First-line Pharmaceutical Treatments
    • Fibrinolytics
    • P2Y12 Inhibitors
    • Glycoprotein Receptor Antagonists
  • Second-Line Pharmaceutical Treatments

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Heart FailureContent Review

 
  • Overview
  • Clinical Features
    • Pathophysiology
    • Compensation
  • Diagnostic Criteria
    • Classifications
    • Exacerbating Factors
  • Non-Pharmaceutical Treatments
  • Pharmaceutical Treatments
    • Nitrate/Hydralazine
    • Ace Inhibitors
    • Angiotensin Receptor Blockers
    • Loop Diuretics
    • Aldosterone Receptor Antagonists
    • Adrenergic Receptor Antagonists

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ShockContent Review

 
  • Overview
  • Classifications
    • Pathophysiology
  • Hypovolemic Shock
  • Cardiogenic Shock
  • Anaphylactic Shock
  • Neurogenic Shock
  • Treatments

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Intro to Infectious DiseasesContent Review

 
  • Intro to Infectious Diseases
    • Overview

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Intro to Infectious DiseasesContent Review

 
  • Identification of Bacteria
    • Shape Classification
    • Gram-Stain Classification
  • Antibiotic Selection
    • Empiric Treatment
    • Data Collection
    • Antibiotic Susceptibility
    • Combination Antibiotic Treatment
  • Common Infections
    • Sites of Infection
  • Treatment Evaluation
  • Antibiotic Use for Surgeries
    • Pre-Operative
    • Intra-Operative
    • Post-Operative
    • Procedure Based Antibiotics
  • Meningitis
    • Overview
    • Clinical Features
    • Pharmaceutical Treatment
  • Peritonitis
    • Primary Peritonitis
    • Secondary Peritonitis

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Management of Care

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Health Promotion and Maintenance

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Targeted score: with , , , , , , ,

Management of Care

Score : Below average

Safety and Infection Control

Score : Below average

Health Promotion and Maintenance

Score : Below average

Psychosocial Integrity

Score : Below average

Basic Care and Comfort

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Pharmacological and Parenteral Therapies

Score : Below average

Reduction of Risk Potential

Score : Below average

Physiological Adaptation

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Kushali

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Scott

PG5 PhamD Program

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Noni

PhamD Program (PG4)

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Gwyneth

Pharmasist (PhamD)

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Each subject review was written by students from Yale University with perfect exam scores. Each subject is condensed into an exceptionally easy-to-learn format with engaging content to more effectively retain concepts.

Pharmacist

Kushali is a P4 pharmacy student at Ernest Mario School of Pharmacy at Rutgers University. Kushali began the program directly out of high school, where she was in the top 10% of her graduating class. She is on track to receive her PharmD degree. She currently has five years of experience working in the retail pharmacy setting. Kushali has also been involved in a research project led by her preceptor during her introductory pharmacy practice experience. In this endeavor, the PharmD candidate conducted a medication use evaluation by assessing almost 300 patient charts for appropriate antibiotic prescribing practices. At the moment, Kushali has just began her advanced pharmacy practice experience and is working at an ambulatory care clinic. Upon graduation, she hopes to pursue a career in medical writing as a PharmD.

PG5 PhamD Program

Scott Yi is a PharmD Program at the Ernest Mario School of Pharmacy at Rutgers University, New Jersey. Scott is a 5th year pharmacy student who's completed medicinal chemistry, as well as various pharmacotherapy modules, classes that are considered to be the most challenging of the curriculum. Scott am a member of iPHO (Industry Pharmacist Organization) newsletter committee, and was active in the annual VIP (Value Industry Pharmacist) Clinical Case Competition the year prior.

PhamD Program (PG4)

Noni Theocharides is a 4th-year pharmacy student pursuing her PharmD degree at the Ernest Mario School of Pharmacy (EMSOP) at Rutgers University, New Jersey. She has excelled academically through her studies and research and professionally in her role in clinical pharmacy and as a professional tutor. Alongside her peers, Noni has held leadership positions clubs like the American Pharmacists Association (APhA) and the Hematology Oncology Pharmacy Association (HOPA). She has published articles in the EMSOP Chronicles – an interdisciplinary journal – and in the Journal of Hematology Oncology Pharmacy (JHOP). Noni has earned Dean’s list throughout her academic career and looks forward to furthering her pharmaceutical knowledge.

Pharmasist (PhamD)

Gwyneth recieved her Bachelors of Arts and Doctorate of Pharmacy from the University of the Pacific School of Pharmacy, California. She is currently working in an independent pharmacy practice. Her professional interests include digital health, medical communications, and exploring fields in the pharmacuetical industry.

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